Baranov V G, Kogan M E, Propp M V, Proimina F I
Probl Endokrinol (Mosk). 1977 Jan-Feb;23(1):60-4.
In the androgen-sterile rats given 10-250 mug of testosterone-propionate there was observed at the early postnatal period a reduction in the LH-RP level in the hypothalamus, of the LH in the hypophysis and the blood, of the weight of the ovaries and of the corporal luteum count in them, as well as an increase in the dopamine level in the anterior portion of the hypothalamus. Klomiphen administration for 5 days in a dose of 20 mug led to the normalization of these indices and to the appearance of ovulation, but failed to restore the capacity to pregnancy. Prolonged klomiphen administration (20 mug every 3 days for a period of 1 month) also failed to restore this capacity.
给雄激素不育大鼠注射10 - 250微克丙酸睾酮后，在出生后早期观察到下丘脑促黄体激素释放多肽（LH - RP）水平降低，垂体和血液中促黄体激素（LH）水平降低，卵巢重量及其中黄体数量减少，同时下丘脑前部多巴胺水平升高。以20微克的剂量给予克罗米酚5天，可使这些指标恢复正常并出现排卵，但未能恢复受孕能力。长期给予克罗米酚（每3天20微克，持续1个月）也未能恢复这种能力。
