Chang Ya-Li, Hu Jun-Ping, Yang Yuan, Zhao Xiao-Dong, Lin Yue, Gao Ming-Xia
School of Nursing, Lanzhou University First Hospital / Key Laboratory for Reproductive Medicine and Embryos of Gansu Province, Lanzhou University, Lanzhou, Gansu 730000, China.
Special Hospital of Reproductive Medicine, Lanzhou University First Hospital / Key Laboratory for Reproductive Medicine and Embryos of Gansu Province, Lanzhou University, Lanzhou, Gansu 730000, China.
Zhonghua Nan Ke Xue. 2018 Nov;24(11):1005-1010.
To explore the influence of body fat percentage (BF%) and body mass index (BMI) on the semen quality of adult males.
A total of 125 randomly selected male infertility patients underwent examinations of semen quality, BMI and BF% on the day of enrollment. With BMI ≥28 kg/m2 as the criterion of obesity, 50 of the patients fell into the category of obesity and 75 into that of non-obesity, while with BF% >25% as the criterion, 69 belonged to the obesity and 56 to the non-obesity type. We compared the semen parameters of the subjects between the obesity and non-obesity groups based on the two criteria and analyzed the correlation of semen quality with age, BF% and BMI.
With BF% as the criterion, the obesity patients, as compared with the non-obesity men, showed significantly lower semen volume (［2.94 ± 1.15］ vs ［3.51 ± 1.27］ ml, P < 0.05), percentage of grade a+b sperm (［33.37 ± 19.80］% vs ［41.87 ± 15.43］%, P < 0.05) and sperm motility (［56.31 ± 22.26］% vs ［64.95 ± 18.22］%, P < 0.05). Similar results were observed with BMI as the criterion in the semen volume (［2.86 ± 1.11］ vs ［3.34 ± 1.26］ ml, P < 0.05), percentage of grade a sperm (［16.33 ± 13.80］% vs ［25.09 ± 15.06］%, P < 0.05), percentage of grade a+b sperm (［30.10 ± 18.43］% vs ［39.80 ± 17.50］%, P < 0.05) and sperm motility (［53.62 ± 21.56］% vs ［62.83 ± 20.47］%, P < 0.05). Age was correlated negatively with sperm motility (r = －0.20,P < 0.05), BF% negatively with the semen volume (r = －0.21, P < 0.05), the percentage of grade a sperm (r = －0.21, P < 0.05) and the percentage of grade a+b sperm (r = －0.18, P <0.05), and BMI negatively with the semen volume (r = －0.26, P < 0.01), percentage of grade a sperm (r = －0.23, P<0.01) and percentage of grade a+b sperm (r = －0.18, P < 0.05). Further multivariate analysis also showed that BF% was negatively correlated with the semen volume and percentage of grade a+b sperm after exclusion of age and other factors.
Obesity affects the semen volume, percentage of grade a sperm, percentage of grade a+b sperm and sperm motility in male infertility patients. And BF% can be used as an indicator in the diagnosis of obesity.
探讨体脂百分比（BF%）和体重指数（BMI）对成年男性精液质量的影响。
共125例随机选取的男性不育患者在入组当天接受精液质量、BMI及BF%检查。以BMI≥28kg/m²作为肥胖标准，50例患者属于肥胖组，75例属于非肥胖组；以BF%>25%作为肥胖标准，69例属于肥胖组，56例属于非肥胖组。我们根据这两个标准比较了肥胖组和非肥胖组受试者的精液参数，并分析了精液质量与年龄、BF%及BMI的相关性。
以BF%为标准，肥胖患者与非肥胖男性相比，精液量显著降低（［2.94±1.15］ vs ［3.51±1.27］ml，P<0.05），a+b级精子百分比（［33.37±19.80］% vs ［41.87±15.43］%，P<0.05）及精子活力（［56.31±22.26］% vs ［64.95±18.22］%，P<0.05）。以BMI为标准时，精液量（［2.86±1.11］ vs ［3.34±1.26］ml，P<0.05）、a级精子百分比（［16.33±13.80］% vs ［25.09±15.06］%，P<0.05）、a+b级精子百分比（［30.10±18.43］% vs ［39.80±17.50］%，P<0.05）及精子活力（［53.62±21.56］% vs ［62.83±20.47］%，P<0.05）也有类似结果。年龄与精子活力呈负相关（r =－0.20，P<0.05），BF%与精液量（r =－0.21，P<0.05）、a级精子百分比（r =－0.21，P<0.05）及a+b级精子百分比（r =－0.18，P<0.05）呈负相关，BMI与精液量（r =－0.26，P<0.01）、a级精子百分比（r =－0.23，P<0.01）及a+b级精子百分比（r =－0.18，P<0.05）呈负相关。进一步多因素分析还显示，排除年龄及其他因素后，BF%与精液量及a+b级精子百分比呈负相关。
肥胖影响男性不育患者的精液量、a级精子百分比、a+b级精子百分比及精子活力。且BF%可作为肥胖诊断的一项指标。
