Center for Alzheimer's Care, Imaging, and Research, Department of Neurology, University of Utah, Salt Lake City, UT, USA.
Center on Aging, University of Utah, Salt Lake City, UT, USA.
J Clin Exp Neuropsychol. 2020 May;42(4):394-405. doi: 10.1080/13803395.2020.1740654. Epub 2020 Mar 26.
: Reliable change methods can assist neuropsychologists in determining whether observed changes in a patient's performance are clinically meaningful. The current study sought to validate previously published standardized regression-based (SRB) equations for the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Indexes and subtests.: Duff and colleagues's SRB prediction equations, developed from 223 cognitively intact primary care patients, were applied to an independent sample of robustly cognitively intact ( = 129) community-dwelling older adults assessed with the RBANS twice over a one-year period.: Results suggest that the cognitively intact participants in the current validation sample possessed significantly better Observed Follow-up scores than was predicted based on Duff's developmental sample across most RBANS Indexes and many RBANS subtests, though significantly lower Observed Follow-up scores were observed for the Visuospatial/Constructional Index than was predicted. As a result of these findings, the current study calculated updated prediction algorithms for the RBANS Index and subtest scores from the sample of 129 cognitively intact participants.: Duff's 2004 and 2005 SRB prediction equations for the RBANS Index and subtest scores failed to generalize to a sample of cognitively intact community-dwelling participants recruited from senior living centers and independent assisted living facilities. These updated SRB prediction equations - being developed from a more medically "clean" sample of cognitively intact older adults who remained stable over 12 months - have the potential to provide a more accurate assessment of reliable change in an individual patient.
可靠变化方法可以帮助神经心理学家确定患者表现的观察到的变化是否具有临床意义。本研究旨在验证先前发表的基于标准化回归（SRB）的重复评估神经心理状态测试（RBANS）指数和子测试的方程。Duff 及其同事的 SRB 预测方程是从 223 名认知完整的初级保健患者中开发的，这些方程应用于一个独立的认知健全的（=129）社区居住的老年人样本中，这些老年人在一年的时间内两次接受 RBANS 测试。结果表明，目前验证样本中的认知健全参与者在大多数 RBANS 指数和许多 RBANS 子测试中，其观察到的随访得分明显高于基于 Duff 的发展样本的预测得分，尽管在视空间/结构指数上观察到的随访得分明显低于预测得分。由于这些发现，本研究根据 129 名认知健全参与者的样本，为 RBANS 指数和子测试得分计算了更新的预测算法。Duff 于 2004 年和 2005 年提出的基于 SRB 的 RBANS 指数和子测试得分的预测方程无法推广到从高级生活中心和独立辅助生活设施招募的认知健全的社区居住参与者样本。这些更新的 SRB 预测方程——是从认知健全的老年人中更“干净”的样本中开发出来的，这些老年人在 12 个月内保持稳定——有可能为个体患者的可靠变化提供更准确的评估。
