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一例因过度饮酒导致的狭窄型缺血性结肠炎,进行随访以排除结肠癌。

A case of stricture-type ischemic colitis from excessive alcohol consumption, with follow-up to rule out colon cancer.

机构信息

Department of Internal Medicine, Hanawa Kousei Hospital.

Department of Rheumatology, Fukushima Medical University School of Medicine.

出版信息

Fukushima J Med Sci. 2020 Apr 22;66(1):60-66. doi: 10.5387/fms.2019-27. Epub 2020 Mar 24.

Abstract

A 69-year-old man was admitted to Hanawa Kousei Hospital with acute hepatitis attributed to alcohol consumption. His condition improved with conservative treatment. Computed tomography (CT) showed localized thickening of the colonic wall at the splenic flexure;carcinoembryonic antigen level was slightly elevated to 9.7 ng/mL. Colonoscopy (CS) showed an ulcerative lesion in the colonic splenic flexure. Ischemic colitis (IC) and type 4 colon cancer were suspected, but biopsy was not confirmatory. Malignancy could not be ruled out by contrast-enhanced CT;repeat CS showed circumferential stenosis of the colonic splenic flexure. Ischemic colitis was suspected based on changes between the first and second CS. Biopsy histopathology led us to diagnose stricture-type IC. Constipation, but not intestinal obstruction, occurred. Conservative treatment improved the stenosis. Excessive alcohol consumption may lead to IC;imaging studies may be useful to distinguish IC from colon cancer. Since most cases of ischemic colitis can be improved with conservative treatment, patients with stricture-type ischemic colitis may also be treated without surgery early on, with follow-up that includes careful, periodic imaging.

摘要

一位 69 岁男性因饮酒导致急性肝炎入住花轮光生医院。经保守治疗,病情好转。计算机断层扫描(CT)显示脾曲处结肠壁局限性增厚;癌胚抗原水平略有升高至 9.7ng/mL。结肠镜检查(CS)显示结肠脾曲处溃疡性病变。怀疑缺血性结肠炎(IC)和 4 型结肠癌,但活检不具确诊性。增强 CT 不能排除恶性肿瘤;再次 CS 显示结肠脾曲环状狭窄。根据第一次和第二次 CS 的变化,怀疑为缺血性结肠炎。活检组织病理学诊断为狭窄型 IC。出现便秘,但无肠梗阻。保守治疗改善了狭窄。过度饮酒可能导致 IC;影像学研究有助于区分 IC 和结肠癌。由于大多数缺血性结肠炎病例可以通过保守治疗改善,因此早期对于狭窄型缺血性结肠炎患者,可能也无需手术治疗,通过定期仔细的影像学随访即可。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94c9/7269883/3302506c2dd3/2185-4610-66-060-g001.jpg

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