Universidade de São Paulo. São Paulo, São Paulo, Brazil.
Rev Bras Enferm. 2020 Mar 20;73(2):e20180324. doi: 10.1590/0034-7167-2018-0324. eCollection 2020.
To estimate the prevalence of cardiometabolic diseases and their association with polypharmacy in elderly people at the University of the Third Age (Portuguese acronym: UnATI).
A cross-sectional, descriptive, analytical study with 121 elderly patients. The prevalence ratio, Pearson's Chi-square test and Fisher's exact test were used as measures of association.
At the mean age of 68.3, most elderly had at least one cardiometabolic disease (82.6%), of which hypertension was the most prevalent (71.1%), and consumed prescription drugs of continuous use (92.6%). Almost half of the elderly (48.2%) used combinations of drugs, which suggests a high cardiovascular risk. Polypharmacy due to prescription was observed in almost one-third (28.6%) of the sample, associated with the use of antihypertensives (p=0.004), antidiabetics (p=0.000) or lipid-lowering agents (p<0.000).
Clinical guidelines recommend changes in lifestyle, but increased pharmacotherapy prevails in practice, which increases the risk of adverse events, especially in old age.
评估老年大学（葡萄牙语缩写：UnATI）人群中心血管代谢疾病的患病率及其与多种药物治疗的关系。
这是一项横断面、描述性、分析性研究，共纳入 121 名老年患者。使用患病率比、皮尔逊卡方检验和 Fisher 确切检验作为关联的度量指标。
在平均年龄为 68.3 岁时，大多数老年人至少患有一种心血管代谢疾病（82.6%），其中高血压最常见（71.1%），并持续使用处方药（92.6%）。近一半的老年人（48.2%）使用了药物联合治疗，这表明他们存在较高的心血管风险。由于处方而导致的多种药物治疗在样本中约占三分之一（28.6%），与使用抗高血压药（p=0.004）、降糖药（p=0.000）或降脂药（p<0.000）有关。
临床指南建议改变生活方式，但实际上增加了药物治疗，这增加了不良事件的风险，尤其是在老年人群中。
