Sánchez Ramiro, Pessana Franco, Lev Gabriel, Mirada Micaela, Mendiz Oscar, Ramírez Agustín, Fischer Edmundo Cabrera
Metabolic Unit and Hypertension Unit, University Hospital, Favaloro Foundation, Buenos Aires, Argentina.
IMETTYB Favaloro University-CONICET, Solís 453 (1078), Buenos Aires, Argentina.
High Blood Press Cardiovasc Prev. 2020 Apr;27(2):165-174. doi: 10.1007/s40292-020-00371-4. Epub 2020 Mar 25.
Measurement of central (aortic) systolic blood pressure has been shown to provide reliable information to evaluate target organ damage. However, non-invasive central blood pressure measurement procedures are still under analysis.
To compare human pressure waveforms invasively obtained in the aorta, with the corresponding waveforms non-invasively recorded using an oscillometric device (Mobil-O-Graph).
In this research were included 20 subjects in which invasive percutaneous coronary interventions were performed. They were 10 males (68 ± 12 y. o.
, BMI: 27.4 ± 4.6 kg/m) and 10 females (77 ± 8 y. o.
, BMI: 28.5 ± 5.3 kg/m). During the invasive aortic pressure recording, a synchronized non-invasive Mobil-O-Graph acquisition beat by beat and reconstructed central pressure wave was performed. Both, invasive and non-invasive pressure waves were digitized and stored for subsequent analysis and calculations. A computerized interpolation procedure was developed in our laboratory to compare these pressure waves.
A significant correlation between Mobil-O-Graph central blood pressure measurements and the corresponding invasive values was found in males (r < 0.81; p < 0.01) and females (r < 0.93; p < 0.01). However, in both genders, the slope of the regression lines was lesser than 1 (males: y = 0.7354x + 18.998; females: y = 0.9835x + 2.8432). In the whole population (n = 20), a significant correlation between Mobil-O-Graph central blood pressure measurements and the corresponding invasive values was found (r < 0.89; p < 0.01) and the regression line was lesser than 1 (y = 0.9774x + 1.7603).
In this research, a high correlation between invasive central blood pressure values and those measured with the Mobil-O-Graph device was found in males, females and the whole population. However, a sub estimation of Mobil-O-Graph central blood pressure values was observed.
已证明测量中心（主动脉）收缩压可为评估靶器官损害提供可靠信息。然而，无创中心血压测量方法仍在分析之中。
比较通过侵入性方法在主动脉获取的人体压力波形与使用示波装置（Mobil - O - Graph）无创记录的相应波形。
本研究纳入了20例行侵入性经皮冠状动脉介入治疗的受试者。其中男性10名（年龄68 ± 12岁，体重指数：27.4 ± 4.6 kg/m²），女性10名（年龄77 ± 8岁，体重指数：28.5 ± 5.3 kg/m²）。在侵入性记录主动脉压力期间，同步进行无创Mobil - O - Graph逐搏采集并重建中心压力波。侵入性和无创压力波均进行数字化处理并存储，以供后续分析和计算。我们实验室开发了一种计算机化插值程序来比较这些压力波。
在男性（r < 0.81；p < 0.01）和女性（r < 0.93；p < 0.01）中，发现Mobil - O - Graph中心血压测量值与相应的侵入性测量值之间存在显著相关性。然而，在两种性别中，回归线的斜率均小于1（男性：y = 0.7354x + 18.998；女性：y = 0.9835x + 2.8432）。在整个研究人群（n = 20）中，发现Mobil - O - Graph中心血压测量值与相应的侵入性测量值之间存在显著相关性（r < 0.89；p < 0.01），且回归线斜率小于1（y = 0.9774x + 1.7603）。
在本研究中，在男性、女性及整个研究人群中，发现侵入性中心血压值与使用Mobil - O - Graph装置测量的值之间存在高度相关性。然而，观察到Mobil - O - Graph中心血压值存在低估情况。
