Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, CESPU , Gandra, Portugal.
UCIBIO/REQUIMTE, MedTech-Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto , Porto, Portugal.
Psychol Health Med. 2021 Feb;26(2):242-259. doi: 10.1080/13548506.2020.1741655. Epub 2020 Mar 27.
This study aimed to evaluate the psychosocial differences between patients with psoriasis in different phases of the disease. Seventy-one patients in exacerbation and 83 in remission were evaluated regarding sociodemographic, clinical and psychological variables, on the premise that the visibility of lesions (exacerbation phase) may impact the emotional regulation and embitterment. A regression analysis was performed to identify the variables that contribute to explain embitterment: a diagnosis of anxiety and/or depression and psoriasis severity are the identified ones. The results point to higher values of emotional dysregulation and embitterment, as well as more critical clinical variables in patients with active disease, namely, alcohol and coffee consumption, smoking and less satisfaction with current treatment, more diagnoses and more family history of anxiety and depression, more psychology/psychiatry consultations and more use of anxiolytics and antidepressants. However, only the results referring to alcohol consumption and embitterment are significantly higher in subjects in the exacerbation phase of the disease. Particular clinical attention should be provided to patients in exacerbation phase regarding psychotherapeutic approach.
本研究旨在评估处于疾病不同阶段的银屑病患者的心理社会差异。在病变的可见性（加重期）可能影响情绪调节和痛苦感知的前提下，评估了 71 名处于加重期和 83 名处于缓解期的患者的社会人口学、临床和心理变量。进行了回归分析以确定有助于解释痛苦的变量：焦虑和/或抑郁的诊断以及银屑病的严重程度是确定的变量。结果表明，活跃期患者的情绪失调和痛苦程度更高，以及更严重的临床变量，即酒精和咖啡的摄入、吸烟以及对当前治疗的满意度降低、更多的诊断和焦虑和抑郁的家族史更多、更多的心理/精神病学咨询以及更多地使用抗焦虑药和抗抑郁药。然而，只有在疾病加重期的患者中，酒精摄入和痛苦感知的结果明显更高。应特别关注处于加重期的患者，以提供心理治疗方法。
