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患有中重度银屑病的患者与更高的抑郁和焦虑症状风险相关:300 名西班牙银屑病患者的多元研究结果。

Patients with Moderate to Severe Psoriasis Associate with Higher Risk of Depression and Anxiety Symptoms: Results of a Multivariate Study of 300 Spanish Individuals with Psoriasis.

机构信息

Department of Dermatology, Hospital del Mar, Barcelona, Spain.

出版信息

Acta Derm Venereol. 2019 Apr 1;99(4):417-422. doi: 10.2340/00015555-3114.

DOI:10.2340/00015555-3114
PMID:30628634
Abstract

Psoriasis is a chronic skin disease associated with considerable physical and psychological comorbidities. Stress and emotional disturbances have been implicated in both triggering the onset and exacerbation of psoriasis. In order to determine the level of perceived stress and mood alterations in patients with psoriasis and their association with disease severity, 300 individuals completed diverse validated questionnaires assessing stress and psychological mood. Evaluation of perception of disease was also measured. A significant association between psoriasis severity and mood, emotional disturbances and an impact on assessments of the quality of life were observed. Particularly, Montgomery-Asberg Depression Rating Scale, Hamilton Rating Scale and Hospital Anxiety and Depression Scale for Depression detected a significant risk for depression in relation to the disease severity. The association between depression features, anxiety and perceived stress with psoriasis severity is important and can influence the appropriate management of psoriasis.

摘要

银屑病是一种慢性皮肤病,与相当多的躯体和心理合并症相关。压力和情绪紊乱与银屑病的发病和恶化均相关。为了确定银屑病患者感知的压力水平和情绪变化,及其与疾病严重程度的关系,300 名个体完成了不同的经过验证的评估压力和心理情绪的问卷。疾病感知的评估也进行了测量。观察到银屑病严重程度与情绪、情绪紊乱之间存在显著相关性,对生活质量的评估也有影响。特别是,蒙哥马利-艾斯伯格抑郁评定量表、汉密尔顿抑郁评定量表和医院焦虑抑郁量表在评估与疾病严重程度相关的抑郁风险方面具有显著意义。抑郁特征、焦虑和感知压力与银屑病严重程度之间的关联很重要,并可能影响银屑病的适当管理。

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