三重心质量指数作为超重青少年胰岛素抵抗预测指标的研究：一项横断面研究。
Tri-ponderal mass index as a tool for insulin resistance prediction in overweight adolescents: A cross-sectional study.
机构信息
Department of Physical Education, Center of Health Sciences, State University of Maringa-UEM, Maringa, Brazil; Multidisciplinary Centre of Obesity Studies-NEMO, State University of Maringa, Maringa, Brazil.
Department of Physical Education, Center of Health Sciences, State University of Maringa-UEM, Maringa, Brazil; Research Group on Systemic Arterial Hypertension, Arterial Stiffness and Vascular Aging-GPHARV, State University of Maringa-UEM, Maringa, Brazil.
出版信息
Nutrition. 2020 Jun;74:110744. doi: 10.1016/j.nut.2020.110744. Epub 2020 Jan 24.
OBJECTIVE
The aims of this study were to assess the capacity of tri-ponderal mass index (TMI) to screen and predict insulin resistance (IR) in overweight Brazilian adolescents, comparing it with body mass index (BMI) predictive capacity; and to verify the IR predictive capacity of other assessment tools such as waist circumference (WC), and waist-to-height ratio (WHR).
METHODS
A cross-sectional study was carried out with 217 overweight adolescents, from both sexes, between 12 and 18 y of age. The participants were classified as having IR according to a previous established cutoff point of ≤3.16. IR was determined by the homeostasis model assessment of insulin resistance. The other assessment tools were measured with standard protocols.
RESULTS
There was no difference between TMI and BMI to explain the presence of IR. In girls, BMI presented a slightly better predictive capacity to explain IR than TMI. Moreover, WC was reported to be the most effective IR screening methods for girls. Receiver operating characteristic curves showed that TMI and BMI presented similar values of sensibility and specificity for boys. Nevertheless, BMI had a better sensibility and TMI had a better specificity for girls. Interestingly, WC demonstrated a strong sensibility for both sexes.
CONCLUSIONS
TMI did not present a superior predictive accuracy for IR screening in overweight Brazilian adolescents when compared with BMI. TMI and BMI presented similar values of sensitivity and specificity for boys and WC a slightly superior IR predictive capacity for girls.
目的
本研究旨在评估三重点质量指数（TMI）筛查和预测超重巴西青少年胰岛素抵抗（IR）的能力，将其与体重指数（BMI）的预测能力进行比较；并验证其他评估工具如腰围（WC）和腰高比（WHR）对 IR 的预测能力。
方法
对 217 名 12 至 18 岁的超重青少年进行了横断面研究。根据先前确定的≤3.16 截定点，将参与者分为存在 IR 组。IR 采用稳态模型评估胰岛素抵抗进行测定。其他评估工具采用标准方案进行测量。
结果
TMI 与 BMI 之间不存在差异，无法解释 IR 的存在。在女孩中，BMI 对解释 IR 的预测能力略优于 TMI。此外，WC 是女孩中最有效的 IR 筛查方法。受试者工作特征曲线显示，TMI 和 BMI 对男孩的敏感性和特异性具有相似的值。然而，BMI 对女孩的敏感性更好，而 TMI 对女孩的特异性更好。有趣的是，WC 对两性均具有较强的敏感性。
结论
与 BMI 相比，TMI 并未在超重巴西青少年中表现出对 IR 筛查的更高预测准确性。TMI 和 BMI 对男孩的敏感性和特异性具有相似的值，而 WC 对女孩的 IR 预测能力略高。
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