Abdel Razek Ahmed Abdel Khalek, Elsebaie Nermeen A, Zamora Carlos, Castillo Mauricio
From the Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, Egypt.
Department of Radiology. Alexandria Faculty of Medicine, Alexandria, Egypt.
J Comput Assist Tomogr. 2020 May/Jun;44(3):356-369. doi: 10.1097/RCT.0000000000001010.
Neuronal and mixed glioneuronal tumors represent a group of neoplasms with varying degrees of neural and glial elements. Their age of presentation varies, but they are most commonly seen in children and young adults. With the exception of anaplastic ganglioglioma and other atypical variants, most lesions are low grade; however, they can have significant morbidity because of seizures, mass effect, or difficult to treat hydrocephalus. Although many tumors show overlapping clinical and imaging features, some have relatively distinctive imaging characteristics that may aid in narrowing the differential diagnosis. In this review, we discuss relevant clinical and pathologic characteristics of these tumors and provide an overview of conventional and advanced imaging features that provide clues as to the diagnosis.
神经元性和混合性神经胶质神经元肿瘤是一组具有不同程度神经和胶质成分的肿瘤。它们的发病年龄各不相同,但最常见于儿童和年轻人。除间变性节细胞胶质瘤和其他非典型变体外,大多数病变为低级别;然而,由于癫痫发作、占位效应或难以治疗的脑积水,它们可能具有显著的发病率。尽管许多肿瘤表现出重叠的临床和影像学特征,但有些肿瘤具有相对独特的影像学特征,可能有助于缩小鉴别诊断范围。在本综述中,我们讨论了这些肿瘤的相关临床和病理特征,并概述了有助于诊断的传统和先进影像学特征。