National Alzheimer's Coordinating Center, University of Washington, Seattle, WA.
Alzheimer Dis Assoc Disord. 2020 Apr-Jun;34(2):175-177. doi: 10.1097/WAD.0000000000000376.
The proprietary neuropsychological tests (Form C1) of the National Alzheimer's Coordinating Center (NACC) Uniform Data Set were replaced with nonproprietary versions (Form C2) chosen to closely model their proprietary counterparts. Correlations between analogous test pairs as measured in previous work were good (0.68-0.78), but it is unclear whether the paired tests represent the same set of common factors of cognition or if important factors specific to C1 or C2 only exist. The authors performed multiple factor analysis to analyze correlated C1 and C2 data. They included participants who completed both neuropsychological batteries within 1 year with no change in cognitive status. They found that the C1 and C2 neuropsychological test pairs are strongly related and are represented by the same principal factors. These findings support the use of the C2 test results in conjunction with C1 in longitudinal analyses of NACC data.
专有神经心理学测试（NACC 统一数据集的 Form C1）已被替换为非专有版本（Form C2），以更接近地模拟其专有版本。在之前的研究中，类似测试对之间的相关性很好（0.68-0.78），但不清楚配对测试是否代表认知的相同一组共同因素，或者仅 C1 或 C2 特有的重要因素是否存在。作者进行了多元因子分析来分析相关的 C1 和 C2 数据。他们包括了在 1 年内完成了两次神经心理学测试且认知状态没有变化的参与者。他们发现，C1 和 C2 神经心理学测试对之间具有很强的相关性，并且由相同的主要因素表示。这些发现支持在 NACC 数据的纵向分析中同时使用 C2 测试结果和 C1。
