IRCCS Mondino Foundation, Pavia, Italy.
Department of Neurology IC, Oasi Research Institute - IRCCS, Troina, Italy.
Alzheimers Res Ther. 2022 Aug 19;14(1):113. doi: 10.1186/s13195-022-01056-x.
Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer's disease. A major concern is represented by the heterogeneity of the neuropsychological batteries currently adopted in memory clinics and healthcare centers. The current study aimed to solve this issue.
Following the initiative of the University of Washington's National Alzheimer's Coordinating Center (NACC), we presented the Italian adaptation of the Neuropsychological Test Battery of the Uniform Data Set (I-UDSNB). We collected data from 433 healthy Italian individuals and employed regression models to evaluate the impact of demographic variables on the performance, deriving the reference norms.
Higher education and lower age were associated with a better performance in the majority of tests, while sex affected only fluency tests and Digit Span Forward.
The I-UDSNB offers a valuable and harmonized tool for neuropsychological testing in Italy, to be used in clinical and research settings.
神经心理学测试在阿尔茨海默病的诊断和监测中起着至关重要的作用。目前在记忆诊所和医疗中心使用的神经心理学测试组合存在异质性，这是一个主要关注点。本研究旨在解决这一问题。
我们遵循华盛顿大学国家阿尔茨海默病协调中心（NACC）的倡议，展示了神经心理学测试成套工具的意大利语改编版（I-UDSNB）。我们收集了 433 名健康意大利个体的数据，并采用回归模型评估了人口统计学变量对表现的影响，得出了参考规范。
在大多数测试中，较高的教育程度和较低的年龄与更好的表现相关，而性别仅影响流畅性测试和数字跨度向前。
I-UDSNB 为意大利的神经心理学测试提供了一个有价值且协调一致的工具，可用于临床和研究环境。
