Paumgartner G
Radiologe. 1977 Feb;17(2):58-63.
Generation of bile flow in humans depends mainly on two transport mechanisms of the hepatocyte. One of these is responsible for secretion of bile acids, the other for transport of sodium into the bile canaliculi. Accordingly, a bile acid dependent fraction of hepatocytic bile can be distinguished from a bile acid independent fraction. Many endogenous and exogenous substances, including x-ray contrast media, are secreted into hepatocytic bile by more or less specific transport systems. The bile produced by the liver cells is then modified by admixture of ductular bile and by reabsorptive processes in the biliary passages and in the gallbladder. Increased knowledge about these mechanisms represents one of the requirements for progress in oral and intravenous cholangiography.
人体胆汁流动的产生主要取决于肝细胞的两种转运机制。其中一种负责胆汁酸的分泌，另一种负责将钠转运到胆小管中。因此，肝细胞胆汁中胆汁酸依赖性部分可与胆汁酸非依赖性部分区分开来。许多内源性和外源性物质，包括X线造影剂，通过或多或少特定的转运系统分泌到肝细胞胆汁中。肝细胞产生的胆汁随后通过与胆小管胆汁混合以及在胆管和胆囊中的重吸收过程而发生改变。对这些机制的深入了解是口服和静脉胆管造影取得进展的必要条件之一。
