Strasberg S M
Alcohol Clin Exp Res. 1981 Jan;5(1):119-24. doi: 10.1111/j.1530-0277.1981.tb04874.x.
The effects of ethanol on bile formation have been studied in the rat, dog, and man, in both acute and chronic models. The acute and chronic effects differ. Given acutely, ethanol suppresses bile flow and bile acid secretion rate. Chronic administration appears to increase both components of canalicular flow and bile acid secretion rate. Intestinal and hepatic actions are probably involved in the latter effect. Secretion of other biliary lipids and diagnostic anions are also reduced by ethanol.
乙醇对胆汁形成的影响已在大鼠、狗和人类身上，通过急性和慢性模型进行了研究。急性和慢性影响有所不同。急性给予乙醇会抑制胆汁流量和胆汁酸分泌率。慢性给药似乎会增加胆小管流量的两个组成部分以及胆汁酸分泌率。后者的作用可能涉及肠道和肝脏的作用。乙醇还会降低其他胆汁脂质和诊断性阴离子的分泌。
