Pierson Leah, Gibert Sophia, Berkman Benjamin, Danis Marion, Millum Joseph
MD-PhD Program, Harvard Medical School, Boston, Massachusetts, USA
PhD Program in Philosophy, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
J Med Ethics. 2021 Nov;47(11):740-743. doi: 10.1136/medethics-2019-105766. Epub 2020 Mar 27.
Hundreds of millions of rare biospecimens are stored in laboratories and biobanks around the world. Often, the researchers who possess these specimens do not plan to use them, while other researchers limit the scope of their work because they cannot acquire biospecimens that meet their needs. This situation raises an important and underexplored question: how should scientists allocate biospecimens that they do not intend to use? We argue that allocators should aim to maximise the social value of the research enterprise when allocating scarce biospecimens. We provide an ethical framework for assessing the social value of proposed research projects and describe how the framework could be implemented.
全球各地的实验室和生物样本库中储存着数亿份珍稀生物样本。通常,拥有这些样本的研究人员并不打算使用它们,而其他研究人员则因无法获取满足自身需求的生物样本而限制了工作范围。这种情况引发了一个重要且未得到充分探讨的问题:科学家应如何分配他们不打算使用的生物样本?我们认为,分配者在分配稀缺的生物样本时应旨在使研究事业的社会价值最大化。我们提供了一个用于评估拟议研究项目社会价值的伦理框架,并描述了该框架的实施方式。