Ogishima Soichi
Advanced Research Center for Innovations in Next-Generation Medicine/Tohoku Medical Megabank Organization, Tohoku University.
Gan To Kagaku Ryoho. 2022 Feb;49(2):125-128.
Biobanks are biorepositories that collect and store biospecimens. Biobanks obtain the consent of the donor for the use of the biospecimens in a wide range of research with trust, and provide them for medical research after review of the research plan. In recent years, the importance of biobanks has increased dramatically as countries compete fiercely in research to realize genomic medicine. This is because genomic medicine is a personalized health care stratified by the patient's constitution, that is, genomic information, and its research and development requires large-scale biospecimens from hundreds of thousands to tens of millions of people, genomic and omics data obtained from the analysis, and medical data. Biobanks and their networks are being established abroad and in Japan, and this paper will start with an overview of biobanks and introduce the establishment of biobank networks in Japan.
生物样本库是收集和存储生物样本的生物储存库。生物样本库在获得捐赠者同意的情况下,以信任为基础,将生物样本用于广泛的研究,并在审查研究计划后将其提供用于医学研究。近年来,随着各国在实现基因组医学的研究中激烈竞争,生物样本库的重要性急剧增加。这是因为基因组医学是一种根据患者体质(即基因组信息)进行分层的个性化医疗保健,其研发需要来自数十万至数千万人的大规模生物样本、从分析中获得的基因组和组学数据以及医学数据。国外和日本都在建立生物样本库及其网络,本文将首先概述生物样本库,并介绍日本生物样本库网络的建立情况。