Raphael M, Chastang C, Binet J L
Département d'Hématologie, CHU Pitié-Salpêtrière, Paris, France.
Nouv Rev Fr Hematol (1978). 1988;30(5-6):377-8.
Four hundred and ninety-three bone marrow biopsies from CLL patients were analysed on the basis of non diffuse versus diffuse bone marrow lymphocytic infiltration patterns. In each clinical stage A, B, and C there were non significant differences in survival rates according to the bone marrow pattern. However in stage A studying the evolution to stage B or C, a significant difference between patients with non diffuse and diffuse pattern was observed.