Burhenn Peggy, Sun Can-Lan, Scher Kevin S, Hsu Joyce, Pandya Punita, Chui Ching-Yi, Arsenyan Anait, Mitani Dale, Morrison Rachel, Katheria Vani, Hurria Arti
City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA.
J Geriatr Oncol. 2020 Sep;11(7):1108-1114. doi: 10.1016/j.jgo.2020.03.008. Epub 2020 Mar 25.
Older adults with cancer are at higher risk for costly and potentially dangerous hospital readmissions. Identifying risk factors for readmission in this population is important for future prevention of readmission.
Hospital discharges among patients ≥ 65 years with solid tumors on non-surgical services from 2006-2011 were reviewed in this matched case-control study. We abstracted patient/cancer characteristics; functional status; fall risk; chemotherapy line; comorbidities; laboratory values; discharge parameters; and miscellaneous information (Do Not Resuscitate Order, pain scores) from medical records. Conditional logistic regression was used for univariate and multivariable analysis.
This analysis included 184 case-patients readmitted within 30 days after discharge from the index admission and 184 sex- and age-matched control-patients discharged from index admission within three months of the cases with no readmission. Cases and controls had no differences in terms of primary cancer type, treatment, and index admission reason. Cases were more likely to have abnormal hemoglobin, albumin, sodium, and SGOT on discharge. Compared to those with ≤1 abnormal laboratory test, patients with 2 or more abnormal test results were 3 times more likely to be readmitted within 30 days.
This study demonstrated that older adults with cancer who had at least 2 abnormal laboratory results (hemoglobin, albumin, sodium, and SGOT) at discharge were 3 times more likely to be readmitted within 30 days compared to those with ≤1 abnormal results. These laboratory values may be predictive of the risk of readmission, and should be monitored before discharge to potentially prevent readmission.
老年癌症患者再次入院的费用更高,且存在潜在危险。识别该人群再次入院的风险因素对未来预防再次入院很重要。
在这项匹配病例对照研究中,回顾了2006年至2011年非手术科室≥65岁实体瘤患者的出院情况。我们从病历中提取了患者/癌症特征、功能状态、跌倒风险、化疗疗程、合并症、实验室检查值、出院参数以及其他信息(不要复苏医嘱、疼痛评分)。使用条件逻辑回归进行单变量和多变量分析。
该分析纳入了184例在首次入院出院后30天内再次入院的病例患者,以及184例与病例性别和年龄匹配的对照患者,这些对照患者在病例出院后三个月内从首次入院出院且未再次入院。病例组和对照组在原发性癌症类型、治疗方法和首次入院原因方面没有差异。病例组患者出院时血红蛋白、白蛋白、钠和谷草转氨酶更有可能异常。与实验室检查结果异常≤1项的患者相比,2项或更多异常检查结果的患者在30天内再次入院的可能性高出3倍。
本研究表明,出院时至少有2项实验室检查结果(血红蛋白、白蛋白、钠和谷草转氨酶)异常的老年癌症患者,与异常结果≤1项的患者相比,在30天内再次入院的可能性高出3倍。这些实验室检查值可能预示再次入院风险,在出院前应进行监测,以潜在地预防再次入院。