Sun Guo-Hai, Wang Xun, Han You-Feng, Wen Bao-Jie, Dai Yu-Tian, Shi Liang
Department of Urology and Andrology,Drum Tower Hospital Affiliated to Nanjing University School of Medicine, Nanjing, Jiangsu 210008, China.
Department of Diagnostic Ultrasound, Drum Tower Hospital Affiliated to Nanjing University School of Medicine, Nanjing, Jiangsu 210008, China.
Zhonghua Nan Ke Xue. 2019 Jul;25(7):608-612.
To compare the hemodynamic indexes of penile cavernosal arteries in different phases of penile erection and determine the optimal time for color Doppler ultrasonography of the penis.
Forty healthy adult male volunteers with normal erectile function received intracavernous injection of 10 μg Alprostadil together with visual and auditory stimuli. Within the next 30 minutes, we monitored dynamically the blood flow in the bilateral penile cavernosal arteries, and recorded and compared the peak systolic velocity (PSV), end diastolic velocity (EDV) and resistance index (RI) in the phases of latency, tumescence, full erection and rigid erection.
Fourteen of the subjects experienced latency, tumescence and full erection only, but failed to achieve rigid erection. PSV and RI were significantly higher while EDV remarkably lower in the tumescence and full erection phases than in the latency phase (all P < 0.01). Statistically significant differences were observed between the tumescence and full erection phases in EDV and RI (both P < 0.01) but not in PSV (P > 0.05). Among the 26 males that achieved rigid erection, PSV, EDV and RI showed significant differences between the full and rigid erection phases (all P < 0.01), but not between the left and right cavernosal arteries in the same phase (P > 0.05).
The blood flow in the penile cavernosal arteries changes dynamically in the process of penile erection, and the hemodynamic indexes obtained in the full erection phase can better reflect the function of penile cavernous vessels.
比较阴茎勃起不同阶段阴茎海绵体动脉的血流动力学指标，确定阴茎彩色多普勒超声检查的最佳时间。
40名勃起功能正常的健康成年男性志愿者接受海绵体内注射10μg前列地尔，并给予视觉和听觉刺激。在接下来的30分钟内，动态监测双侧阴茎海绵体动脉的血流情况，记录并比较潜伏期、肿胀期、完全勃起期和坚硬勃起期的收缩期峰值流速（PSV）、舒张末期流速（EDV）和阻力指数（RI）。
14名受试者仅经历了潜伏期、肿胀期和完全勃起期，未达到坚硬勃起。肿胀期和完全勃起期的PSV和RI显著高于潜伏期，而EDV显著低于潜伏期（均P<0.01）。EDV和RI在肿胀期和完全勃起期之间存在统计学显著差异（均P<0.01），但PSV无差异（P>0.05）。在达到坚硬勃起的26名男性中，完全勃起期和坚硬勃起期的PSV、EDV和RI存在显著差异（均P<0.01），但同一阶段左右海绵体动脉之间无差异（P>0.05）。
阴茎勃起过程中阴茎海绵体动脉血流呈动态变化，完全勃起期获得的血流动力学指标能更好地反映阴茎海绵体血管功能。
