Adoubi K A, Soya E, Bamba K D, Koffi F, N'Cho-Mottoh M P, Diby F, Gnaba A, Konin C
Institut de cardiologie d'Abidjan, Abidjan, Cote d'Ivoire; Université de Bouaké, Bouaké, Cote d'Ivoire.
Institut de cardiologie d'Abidjan, Abidjan, Cote d'Ivoire.
Ann Cardiol Angeiol (Paris). 2020 Apr;69(2):74-80. doi: 10.1016/j.ancard.2020.03.002. Epub 2020 Mar 27.
The aim of our work was to appreciate the importance of comorbidities of heart failure individually and globally in patients hospitalized at the Cardiology Institute of Abidjan.
This was a prospective cohort study of adult heart failure patients hospitalized from January to December 2015, and followed up over 12 months. Co-morbidities were analysed through their prevalence, their relationship with the etiologies, and their impact on the prognosis.
Three hundred and two patients (mean age: 55.5±16.9 years, 61.6 % male) were recruited. High blood pressure, anaemia and kidney dysfunction were the most common co-morbidities (48 %, 43.7 % and 41.3 % respectively). There was an average of 3.4±1.8 comorbidities per patient with an increase in the number of comorbidities with age (P<0.05) and a more frequent association with hypertensive and ischemic heart disease (P<0.001). During the one-year follow-up, 96 patients died. Apart from hepatic dysfunction (RR=1.97, 95 % CI [1,19-3.25], P=0.008, a high score of Charlson index appeared as a risk factor of death as much in univariate analysis (RR=4.15 95 % CI [2.32-7.41], P<0.001), as in multivariate analysis according to the Cox model (RR=2.48. 95 % CI [1.08-5.09], P=0.03) confirmed by Kaplan Meier curves (P<0.001).
Comorbidities are common in our heart failure patients and significantly affect their prognosis.
我们研究的目的是分别从个体和整体角度评估阿比让心脏病研究所住院患者心力衰竭合并症的重要性。
这是一项对2015年1月至12月住院的成年心力衰竭患者进行的前瞻性队列研究，并随访12个月。通过合并症的患病率、与病因的关系及其对预后的影响进行分析。
招募了302例患者（平均年龄：55.5±16.9岁，男性占61.6%）。高血压、贫血和肾功能不全是最常见的合并症（分别为48%、43.7%和41.3%）。每位患者平均有3.4±1.8种合并症，合并症数量随年龄增加（P<0.05），且与高血压和缺血性心脏病的关联更频繁（P<0.001）。在一年的随访中，96例患者死亡。除肝功能不全外（RR=1.97，95%CI[1.19 - 3.25]，P=0.008），在单因素分析中，高Charlson指数得分与死亡风险因素一样显著（RR=4.15，95%CI[2.32 - 7.41]，P<0.001），在根据Cox模型进行的多因素分析中也是如此（RR=2.48，95%CI[1.08 - 5.09]，P=0.03），Kaplan Meier曲线也证实了这一点（P<0.
