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使用包含缺陷层的一维二进制光子晶体检测和感应血红蛋白。

Detection and sensing of hemoglobin using one-dimensional binary photonic crystals comprising a defect layer.

出版信息

Appl Opt. 2020 Jan 10;59(2):418-424. doi: 10.1364/AO.379041.

Abstract

Believing that the detection of hemoglobin possesses a vital role in the discovery of many diseases, we present in this work a simple method for sensing and detecting hemoglobin based on one-dimensional photonic crystals. Implementing hemoglobin as a defect layer inside the proposed photonic crystal results in a resonant peak evolving within the bandgaps. The strong dependence of these resonant peaks on concentration and the consequent refractive index are the essential bases of the detection process. The role played by these parameters together with the angle of incidence on performance and efficiency of our sensor is demonstrated. In the vicinity of the investigated results, we demonstrate the values of sensitivity, figure of merit (FOM), signal-to-noise ratio (SNR), and resolution to optimize the performance of our sensor. The numerical results show a significant effect of polarization mode on performance of this sensor. For TE polarization with an angle of incidence equal to 45°, we investigated sensitivity of 167, SNR of 0.23, FOM of 0.63, and resolution of 257 nm.

摘要

我们相信血红蛋白的检测在发现许多疾病方面具有重要作用,因此在这项工作中提出了一种基于一维光子晶体的血红蛋白传感和检测的简单方法。将血红蛋白作为所提出的光子晶体中的缺陷层来实现,会导致带隙内出现谐振峰。这些谐振峰对浓度和折射率的强烈依赖是检测过程的基本基础。这些参数以及入射角在传感器性能和效率中的作用都进行了演示。在研究结果的附近,我们展示了灵敏度、品质因数 (FOM)、信噪比 (SNR) 和分辨率的值,以优化传感器的性能。数值结果表明偏振模式对该传感器性能具有显著影响。对于 TE 偏振且入射角等于 45°,我们研究了 167 的灵敏度、0.23 的 SNR、0.63 的 FOM 和 257nm 的分辨率。

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