Schwarzrock R, Endert G
Institut für Nuklearmedizin und spezielle Biophysik, Medizinischen Hochschule Hannover.
Rontgenblatter. 1988 Jul;41(7):288-92.
The 125I fibrinogen test and radionuclide venography have so far been the two standard methods of thrombosis diagnosis via nuclear medicine. Both methods have been developed further as a result of scientific and technical advances in recent years. Direct visualisation of thrombi with the help of 111indium thrombocytes is becoming increasingly important. Direct visualisation of thrombi can be made still easier by antithrombocytic antibodies. In case of contrast medium intolerance, and in diagnosing pulmonary embolism, radionuclide venography can still be useful in combination with lung perfusion scintigraphy, even if nonionic x-ray contrast media are increasingly introduced. The diagnostic possibilities offered by contrast medium venography in respect of precise morphological vascular imaging and function diagnosis, are complementary in many problems of venous diagnostics.
迄今为止,125I纤维蛋白原试验和放射性核素静脉造影术一直是核医学诊断血栓形成的两种标准方法。由于近年来的科技进步,这两种方法都得到了进一步发展。借助111铟标记的血小板直接观察血栓变得越来越重要。抗血小板抗体可使血栓的直接观察更加容易。在对造影剂不耐受的情况下,以及在诊断肺栓塞时,即使非离子型X线造影剂越来越多地被采用,放射性核素静脉造影术与肺灌注闪烁扫描相结合仍可能有用。造影剂静脉造影术在精确的形态学血管成像和功能诊断方面所提供的诊断可能性,在许多静脉诊断问题中具有互补性。