一种新的大鼠淋巴细胞表面标志物：对具有蜗牛血细胞凝集素受体的细胞的特性鉴定与分离
A new rat lymphocyte surface marker: characterization and separation of cells with receptors for Helix pomatia hemagglutinin.
作者信息
Swanborg R H, Hellström U, Perlmann H, Hammarström S, Perlmann P
出版信息
Scand J Immunol. 1977;6(3):235-9. doi: 10.1111/j.1365-3083.1977.tb00389.x.
Thirty-two percent of neuraminidase-treated DA rat spleen lymphocytes and 48% of lymph node lymphocytes possess receptors for Helix pomatia hemagglutinin (HP). Moreover, these HP-receptor-bearing cells can be separated from B cells by affinity chromatography on HP-Sepharose columns. The virtual absence of immunoglobulin (Ig) receptors and the close correlation with reported T-cell content of these lymphoid tissues suggest that HP-receptor lymphocytes are probably T cells and that HP may provide a convenient marker, for both the identification and the purification of rat T lymphocytes.
经神经氨酸酶处理的DA大鼠脾淋巴细胞中，32%以及淋巴结淋巴细胞中48%拥有苹果蜗牛血凝素（HP）受体。此外，这些带有HP受体的细胞可通过在HP-琼脂糖柱上进行亲和层析与B细胞分离。免疫球蛋白（Ig）受体几乎不存在，且与这些淋巴组织中已报道的T细胞含量密切相关，这表明带有HP受体的淋巴细胞可能是T细胞，并且HP可能为大鼠T淋巴细胞的鉴定和纯化提供一种便捷的标志物。
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