Sekhon Simranjeet Singh, Nguyen Phat-Loc, Ahn Ji-Young, Lee Kyeong-Ah, Lee Lyon, Kim Sang Yong, Yoon Hobaek, Park Jihoo, Ko Jung Ho, Kim Yang-Hoon
1School of Biological Sciences, Chungbuk National University, 1 Chungdae-Ro, Seowon-Gu, Cheongju, 28644 Republic of Korea.
2College of Veterinary Medicine, Western University of Health Sciences, 309 E Second Street, Pomona, CA 91766 USA.
Toxicol Environ Health Sci. 2016;8(5):277-289. doi: 10.1007/s13530-016-0287-8. Epub 2017 Jan 4.
Porcine epidemic diarrhea virus (PEDV) is a main etiology causing severe enteric disease in piglets with clinical signs of anorexia, vomiting, diarrhea and dehydration resulting in loss of condition and death within a few days. Historically, PED is one of major causes of loss in swine and remains prevalent in some parts of the world. Even with increase in the available tests for PED diagnosis, which include histological diagnosis; virological diagnosis and serological diagnosis, there is no vaccine or specific treatment for this disease yet. In this mini review, the overview and current situation of PED is described with updated techniques, in an effort to comprehensively discuss and understand the disease characteristics.
猪流行性腹泻病毒(PEDV)是引起仔猪严重肠道疾病的主要病因,其临床症状包括厌食、呕吐、腹泻和脱水,导致仔猪在几天内消瘦并死亡。从历史上看,PED是猪群损失的主要原因之一,在世界某些地区仍然流行。即使用于PED诊断的可用检测方法有所增加,包括组织学诊断、病毒学诊断和血清学诊断,但目前仍没有针对该疾病的疫苗或特效治疗方法。在这篇小型综述中,我们采用最新技术描述了PED的概况和现状,以期全面讨论并了解该疾病的特征。