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原发性肠系膜静脉血栓形成:病例系列

Primary mesenteric vein thrombosis: a case series.

作者信息

Marconato Roberto, Nezi Giulia, Capovilla Giovanni, Moletta Lucia, Baldan Nicola, Canton Silvio Alen, Spirch Saverio, Salvador Renato, Merigliano Stefano

机构信息

Department of Surgical, Oncological and Gastrointestinal Sciences, University of Padova, Padova, Italy.

出版信息

J Surg Case Rep. 2020 Mar 24;2020(3):rjaa016. doi: 10.1093/jscr/rjaa016. eCollection 2020 Mar.

DOI:10.1093/jscr/rjaa016
PMID:32226599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7092682/
Abstract

Mesenteric vein thrombosis (MVT) is a rare condition, often misdiagnosed due to its vague and misleading clinical presentation. It can cause intestinal infarction, peritonitis, and consequently necessitate bowel resection. CT scanning with intravenous contrast enhancement is the gold standard for its diagnosis. Radiologists have an important role in defining the extent of thrombosis and identifying any signs of intestinal infarction influencing the decision whether or not to operate. In patients with no clinical signs of peritonitis or radiological evidence of intestinal infarction, the treatment can be exclusively medical, based on full anticoagulation (initially with low molecular weight heparin, followed by vitamin K antagonists or direct acting oral-anticoagulants). The duration of medical treatment depends on radiological evidence of resolution of thrombosis and the identification of pro-coagulant risk factors.

摘要

肠系膜静脉血栓形成(MVT)是一种罕见疾病,常因其临床表现模糊且具有误导性而被误诊。它可导致肠梗死、腹膜炎,进而需要进行肠切除。静脉注射造影剂增强的CT扫描是其诊断的金标准。放射科医生在确定血栓形成范围以及识别任何影响手术决策的肠梗死迹象方面发挥着重要作用。对于没有腹膜炎临床体征或肠梗死影像学证据的患者,治疗可以完全采用药物治疗,基于充分抗凝(最初使用低分子量肝素,随后使用维生素K拮抗剂或直接作用的口服抗凝剂)。药物治疗的持续时间取决于血栓溶解的影像学证据以及促凝血危险因素的识别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2596/7092682/3da054129398/rjaa016f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2596/7092682/3da054129398/rjaa016f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2596/7092682/3da054129398/rjaa016f1.jpg

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本文引用的文献

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Predictive Risk Factors of Intestinal Necrosis in Patients with Mesenteric Venous Thrombosis: Retrospective Study from a Single Center.肠系膜静脉血栓形成患者肠坏死的预测性风险因素:单中心回顾性研究。
Can J Gastroenterol Hepatol. 2019 May 7;2019:8906803. doi: 10.1155/2019/8906803. eCollection 2019.
2
Diagnostic accuracy of hematological parameters in Acute mesenteric ischemia-A systematic review.血液学参数对急性肠系膜缺血的诊断准确性:系统综述。
Int J Surg. 2019 Jun;66:18-27. doi: 10.1016/j.ijsu.2019.04.005. Epub 2019 Apr 16.
3
Clinical implications of different risk factor profiles in patients with mesenteric venous thrombosis and systemic venous thromboembolism: a population-based study.
肠系膜静脉血栓形成和全身性静脉血栓栓塞症患者不同危险因素特征的临床意义:一项基于人群的研究。
J Thromb Thrombolysis. 2019 May;47(4):572-577. doi: 10.1007/s11239-019-01816-x.
4
Clinical implications of CT findings in mesenteric venous thrombosis at admission.入院时肠系膜静脉血栓形成的CT表现的临床意义
Emerg Radiol. 2018 Aug;25(4):407-413. doi: 10.1007/s10140-018-1601-3. Epub 2018 Mar 28.
5
Editor's Choice - Management of the Diseases of Mesenteric Arteries and Veins: Clinical Practice Guidelines of the European Society of Vascular Surgery (ESVS).编辑推荐——肠系膜动静脉疾病的管理:欧洲血管外科学会(ESVS)临床实践指南
Eur J Vasc Endovasc Surg. 2017 Apr;53(4):460-510. doi: 10.1016/j.ejvs.2017.01.010.