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格雷夫斯病放射性碘治疗后严重放射性甲状腺炎。

Severe radiation thyroiditis after radioactive iodine for treatment of Graves' disease.

机构信息

Department of Endocrinology, Singapore General Hospital, Singapore.

Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital, Singapore.

出版信息

Singapore Med J. 2021 Sep;62(9):486-491. doi: 10.11622/smedj.2020039. Epub 2020 Mar 31.

DOI:10.11622/smedj.2020039
PMID:32227795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9251246/
Abstract

Radiation thyroiditis resulting from radioactive iodine-131 treatment for Graves' disease is an uncommon complication. Although a majority of patients are asymptomatic or manifest mild symptoms that can be managed conservatively, published literature describing severe radiation thyroiditis resulting in significant morbidity is lacking. We herein report on six patients with severe radiation thyroiditis that resulted in hospitalisation, including an unusual complication of myopericarditis.

摘要

放射性碘-131 治疗格雷夫斯病引起的甲状腺炎是一种罕见的并发症。尽管大多数患者无症状或表现为可保守治疗的轻度症状,但缺乏描述严重放射性甲状腺炎导致严重发病率的文献。我们在此报告 6 例严重放射性甲状腺炎导致住院的患者,包括心肌心包炎的罕见并发症。

相似文献

1
Severe radiation thyroiditis after radioactive iodine for treatment of Graves' disease.格雷夫斯病放射性碘治疗后严重放射性甲状腺炎。
Singapore Med J. 2021 Sep;62(9):486-491. doi: 10.11622/smedj.2020039. Epub 2020 Mar 31.
2
Quantitative measurement of thyroid blood flow for differentiation of painless thyroiditis from Graves' disease.甲状腺血流定量测量用于鉴别无痛性甲状腺炎与格雷夫斯病。
Clin Endocrinol (Oxf). 2007 Jul;67(1):41-5. doi: 10.1111/j.1365-2265.2007.02832.x. Epub 2007 Apr 15.
3
Painful acute radiation thyroiditis induced by 131I treatment of Graves' disease.131I治疗格雷夫斯病所致疼痛性急性放射性甲状腺炎
BMJ Case Rep. 2015 Jan 9;2015:bcr2014207670. doi: 10.1136/bcr-2014-207670.
4
Differentiation of thyrotoxicosis induced by thyroid destruction from Graves' disease.甲状腺破坏所致甲状腺毒症与格雷夫斯病的鉴别。
Lancet. 1978 Aug 12;2(8085):344-6. doi: 10.1016/s0140-6736(78)92943-4.
5
Histologic Findings and Cytological Alterations in Thyroid Nodules After Radioactive Iodine Treatment for Graves' Disease: A Diagnostic Dilemma.Graves病放射性碘治疗后甲状腺结节的组织学表现及细胞学改变:诊断难题
Int J Surg Pathol. 2017 Jun;25(4):314-318. doi: 10.1177/1066896917693091. Epub 2017 Feb 15.
6
[Hyperparathyroidism after radioactive iodine therapy for Graves' disease: a case report].[格雷夫斯病放射性碘治疗后甲状旁腺功能亢进:一例报告]
Hinyokika Kiyo. 1983 Nov;29(11):1513-9.
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Graves' hyperthyroidism after postpartum thyroiditis.产后甲状腺炎后的格雷夫斯甲亢
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Thyroid carcinoma after radioactive iodine therapy for Graves' disease.格雷夫斯病放射性碘治疗后发生的甲状腺癌。
World J Surg. 1994 Jul-Aug;18(4):518-21. doi: 10.1007/BF00353753.
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Fine needle aspiration biopsy of the thyroid gland in patients with prior Graves' disease treated with radioactive iodine. Morphologic findings and potential pitfalls.曾接受放射性碘治疗的Graves病患者甲状腺细针穿刺活检。形态学表现及潜在陷阱。
Acta Cytol. 1996 Nov-Dec;40(6):1189-97. doi: 10.1159/000333979.
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Follicular carcinoma of the thyroid following radioactive iodine treatment for Graves' disease.格雷夫斯病放射性碘治疗后发生的甲状腺滤泡癌。
Postgrad Med J. 1988 Nov;64(757):878-80. doi: 10.1136/pgmj.64.757.878.

本文引用的文献

1
Diagnostic Values of Free Triiodothyronine and Free Thyroxine and the Ratio of Free Triiodothyronine to Free Thyroxine in Thyrotoxicosis.游离三碘甲状腺原氨酸、游离甲状腺素及游离三碘甲状腺原氨酸与游离甲状腺素比值在甲状腺毒症中的诊断价值
Int J Endocrinol. 2018 Jun 4;2018:4836736. doi: 10.1155/2018/4836736. eCollection 2018.
2
Radioiodine associated de novo Graves' opthalmopathy in an Asian cohort.亚洲队列中放射性碘相关的新发格雷夫斯眼病
Hell J Nucl Med. 2017 Sep-Dec;20(3):227-231. doi: 10.1967/s002449910606. Epub 2017 Nov 27.
3
Painful Radiation Thyroiditis after I Therapy for Graves' Hyperthyroidism: Clinical Features and Ultrasonographic Findings in Five Cases.放射性碘治疗格雷夫斯病后疼痛性放射性甲状腺炎:5例临床特征及超声表现
Eur Thyroid J. 2016 Sep;5(3):201-206. doi: 10.1159/000448398. Epub 2016 Sep 6.
4
Development of Thyroid-Associated Ophthalmopathy in Patients Who Underwent Total Thyroidectomy.接受全甲状腺切除术后患者甲状腺相关眼病的发生情况
Yonsei Med J. 2015 Sep;56(5):1389-94. doi: 10.3349/ymj.2015.56.5.1389.
5
Radioiodine-Associated Exacerbation of Graves' Orbitopathy in the Japanese Population: Randomized Prospective Study.放射性碘相关 Graves 眼病恶化在日本人群中的发生情况:一项随机前瞻性研究。
J Clin Endocrinol Metab. 2015 Jul;100(7):2700-8. doi: 10.1210/jc.2014-4542. Epub 2015 May 12.
6
Painful acute radiation thyroiditis induced by 131I treatment of Graves' disease.131I治疗格雷夫斯病所致疼痛性急性放射性甲状腺炎
BMJ Case Rep. 2015 Jan 9;2015:bcr2014207670. doi: 10.1136/bcr-2014-207670.
7
Reply to the Letter to the editor: "A comment on Thyrotoxic pericarditis".致编辑的信的回复:“关于甲状腺毒症性心包炎的评论”
Int J Cardiol. 2014 Aug 20;175(3):592-3. doi: 10.1016/j.ijcard.2014.04.106. Epub 2014 Apr 15.
8
Acute pericarditis: unique comorbidity of thyrotoxic crisis with Graves' disease.急性心包炎:格雷夫斯病甲状腺毒症危象的独特合并症。
Int J Cardiol. 2014 Feb 15;171(3):e129-30. doi: 10.1016/j.ijcard.2013.12.042. Epub 2013 Dec 28.
9
Determinants of serum T4 and T3 at the time of diagnosis in nosological types of thyrotoxicosis: a population-based study.不同甲状腺毒症类型患者诊断时血清 T4 和 T3 的决定因素:一项基于人群的研究。
Eur J Endocrinol. 2013 Oct 1;169(5):537-45. doi: 10.1530/EJE-13-0533. Print 2013 Nov.
10
Radioiodine therapy in benign thyroid diseases: effects, side effects, and factors affecting therapeutic outcome.放射性碘治疗良性甲状腺疾病:疗效、副作用以及影响治疗效果的因素。
Endocr Rev. 2012 Dec;33(6):920-80. doi: 10.1210/er.2012-1030. Epub 2012 Sep 7.