甲状腺破坏所致甲状腺毒症与格雷夫斯病的鉴别。
Differentiation of thyrotoxicosis induced by thyroid destruction from Graves' disease.
作者信息
Amino N, Yabu Y, Miyai K, Fujie T, Azukizawa M, Onishi T, Kumahara Y
出版信息
Lancet. 1978 Aug 12;2(8085):344-6. doi: 10.1016/s0140-6736(78)92943-4.
Thyroid function was tested in untreated patients with Graves' disease or thyrotoxic subacute thyroiditis, and in patients with autoimmune thyroiditis who showed postpartum or spontaneous transient thyrotoxicosis. The serum triiodothyronine/thyroxine ratio (T3/T4) was greater than 20 ng/microgram in Graves' disease but less than 20 in all patients with subacute thyroiditis and 9 of 11 patients with autoimmune thyroiditis. Thus, like radioactive iodine uptake, the serum T3/T4 ratio is useful for differentiating destruction-induced thyrotoxicosis from the stimulation-induced hyperthyroidism of Graves' disease.
对未经治疗的格雷夫斯病或甲状腺毒性亚急性甲状腺炎患者，以及出现产后或自发性短暂甲状腺毒症的自身免疫性甲状腺炎患者进行了甲状腺功能测试。格雷夫斯病患者的血清三碘甲状腺原氨酸/甲状腺素比值（T3/T4）大于20 ng/μg，但所有亚急性甲状腺炎患者以及11例自身免疫性甲状腺炎患者中的9例该比值均小于20。因此，与放射性碘摄取一样，血清T3/T4比值有助于区分破坏性甲状腺毒症与格雷夫斯病的刺激性甲状腺功能亢进。
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