药剂师干预对日本2型糖尿病患者多重用药的影响。
Effects of pharmacist intervention on polypharmacy in patients with type 2 diabetes in Japan.
作者信息
Horii Takeshi, Atsuda Koichiro
机构信息
Pharmacy Practice and Science I, Research and Education Center for Clinical Pharmacy, Kitasato University School of Pharmacy, 1-15-1 Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0375, Japan.
Shimokitazawa Hospital, 2-8-16 Kitazawa, Setagaya Ward, Tokyo, 155-0031, Japan.
出版信息
BMC Res Notes. 2020 Mar 30;13(1):183. doi: 10.1186/s13104-020-05032-2.
OBJECTIVE
Investigation of polypharmacy in patients with type 2 diabetes revealed that medications administered according to the patient's symptoms and complaints strongly contributed to polypharmacy. We explored the effects of clinical ward pharmacy service, which evaluated the need for symptomatic treatment, therefore minimizing polypharmacy by reducing inappropriate medications.
RESULTS
The number of drugs (hospitalization vs. discharge: 9 [1-17] vs. 7 [1-16], P < 0.001) and rate of polypharmacy (hospitalization vs. discharge: 75.4% vs. 61.1%, P < 0.001) were significantly lower at discharge. Since hospital admission, the number of drugs increased (n = 6, 11%), remained unchanged (n = 15, 28%), decreased by 1 drug (n = 4, 8%), decreased by 2 drugs (n = 3, 6%), and decreased by more than 2 drugs (n = 25, 47%). Daily drug costs were significantly reduced (hospitalization vs. discharge: $8.3 vs. $6.1, P < 0.001).
目的
对2型糖尿病患者的多重用药情况进行调查发现，根据患者症状和主诉给药是导致多重用药的重要原因。我们探讨了临床病房药学服务的效果，该服务评估了对症治疗的必要性，从而通过减少不适当用药来尽量减少多重用药情况。
结果
出院时药物数量（住院时 vs. 出院时：9 [1 - 17] 种 vs. 7 [1 - 16] 种，P < 0.001）和多重用药率（住院时 vs. 出院时：75.4% vs. 61.1%，P < 0.001）显著降低。自入院以来，药物数量增加的有6例（11%），保持不变的有15例（28%），减少1种药物的有4例（8%），减少2种药物的有3例（6%），减少超过2种药物的有25例（47%）。每日药物费用显著降低（住院时 vs. 出院时：8.3美元 vs. 6.1美元，P < 0.001）。
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