Research and Diagnostic Center for Emerging Infectious Diseases, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Am J Trop Med Hyg. 2020 Jun;102(6):1399-1403. doi: 10.4269/ajtmh.19-0701.
Human angiostrongyliasis is an important foodborne helminthic zoonosis caused by the nematodes of the genus . We describe two parasitologically confirmed cases of ocular angiostrongyliasis, presenting at a tertiary care hospital in Thailand between 2012 and 2018. Parasites were surgically recovered from patients' eyes and morphologically identified as species. DNA analysis allowed identification of . Polymerase chain reaction was used to amplify all or part of the small nuclear ribosomal subunit, the second internal transcribed spacer region, and cytochrome c oxidase subunit 1. The sequences subsequently obtained were highly similar to those of (97-100%). This is the first molecular confirmation that is a causative agent of human angiostrongyliasis in Thailand.
人体旋毛虫病是一种重要的食源性寄生虫动物源性传染病，由旋毛线虫属的线虫引起。我们描述了 2012 年至 2018 年间在泰国一家三级保健医院就诊的两例经寄生虫学证实的眼血管旋毛虫病病例。寄生虫通过手术从患者的眼睛中取出，并通过形态学鉴定为 种。DNA 分析允许鉴定出. 聚合酶链反应用于扩增小核核糖体亚单位、第二内部转录间隔区和细胞色素 c 氧化酶亚单位 1 的全部或部分序列。随后获得的序列与 （97-100%）高度相似。这是首次分子确认 在泰国是人类旋毛虫病的病原体。
