Feng Ying, Nawa Yukifumi, Sawanyavisuth Kittisak, Lv Zhiyue, Wu Zhong-Dao
Department of Histology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Research Affairs, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Korean J Parasitol. 2013 Dec;51(6):613-9. doi: 10.3347/kjp.2013.51.6.613. Epub 2013 Dec 31.
Angiostrongyliasis, caused by Angiostrongylus cantonensis infection, is a food-borne parasitic disease. Its larvae evoke eosinophilic inflammation in the central nervous system, but can also cause pathological changes in the eyes. Among ocular angiostrongyliasis cases, the incidence of optic neuritis is low and only few sporadic reports exist. Some patients with optic neuritis developed obvious hypopsia or even vision loss, which would seriously influence the quality of life of patients. Prompt treatment of optic neuritis caused by A. cantonensis is the key factor for minimizing the incidence of serious complications of this disease. In this review, we first provide a comprehensive overview of ocular angiostrongyliasis, and then focus on the clinical features of optic neuritis caused by A. cantonensis.
广州管圆线虫感染引起的嗜酸性粒细胞增多性脑膜脑炎是一种食源性寄生虫病。其幼虫可引起中枢神经系统嗜酸性粒细胞炎症，也可导致眼部病理改变。在眼部广州管圆线虫病病例中，视神经炎的发病率较低，仅有少数散发病例报道。部分视神经炎患者出现明显视力减退甚至失明，严重影响患者生活质量。及时治疗广州管圆线虫所致视神经炎是降低该病严重并发症发生率的关键因素。在本综述中，我们首先全面概述眼部广州管圆线虫病，然后重点关注广州管圆线虫所致视神经炎的临床特征。
