Jordan Bertrand
UMR 7268 ADÉS, Aix-Marseille, Université /EFS/CNRS ; CoReBio PACA, case 901, Parc scientifique de Luminy, 13288 Marseille Cedex 09, France.
Med Sci (Paris). 2020 Mar;36(3):289-291. doi: 10.1051/medsci/2020028. Epub 2020 Mar 31.
A new company is offering extensive genetic analysis of embryos during an in vitro fertilisation procedure, allowing the derivation of polygenic scores for several diseases and embryo choice based on these results. Polygenic scores, if properly implemented, can indeed have substantial predictive value, and the possibility of embryo choice based on these data has become real, raising a number of practical and ethical problems. ‡.
一家新公司在体外受精过程中提供对胚胎的广泛基因分析,能够得出多种疾病的多基因评分,并根据这些结果进行胚胎选择。如果实施得当,多基因评分确实具有很大的预测价值,基于这些数据进行胚胎选择的可能性已经成为现实,这引发了一些实际和伦理问题。‡