Lewaschow J N, Orsheschkowskij O W
Allunionsforschungsinstitut für Pulmologie des MfG der UdSSR, Leningrad.
Z Erkr Atmungsorgane. 1988;171(3):210-8.
The results of complex studies in 440 patients with disseminated processes are presented. In 135 of them the diagnosis was confirmed by clinical, roentgenologic and laboratory data and by biopsies of skin, muscles and subcutaneous lymph nodes. Transbronchial lung biopsy was performed in 218 patients. It gave positive results in 65% of the cases. Open biopsy of lung was performed in 134 cases. Hemodynamic and gas exchange studies during the operation indicated its insignificant traumatism. Complications (limited hemothorax, partial pneumothorax, subcutaneous emphysema, wound suppuration) were noted in 10 (7.5%) cases in the postoperative period. Pulmonary tests performed three weeks after the operation did not reveal significant changes in the subjects, even those with considerable initial disorders. Open biopsy permitted to verify the diagnosis in 131 (98%) patients. In 52% of these cases the diagnosis did not correspond to the presumed one and considerably influenced the subsequent treatment.
本文呈现了对440例播散性疾病患者进行综合研究的结果。其中135例患者的诊断通过临床、放射学和实验室数据以及皮肤、肌肉和皮下淋巴结活检得以证实。218例患者接受了经支气管肺活检，65%的病例结果呈阳性。134例患者进行了开放性肺活检。手术期间的血流动力学和气体交换研究表明其创伤较小。术后有10例（7.5%）出现并发症（局限性血胸、部分气胸、皮下气肿、伤口化脓）。术后三周进行的肺部检查未发现受试者有明显变化，即使是那些初始疾病较为严重的患者。开放性活检使131例（98%）患者的诊断得以核实。在这些病例中，52%的诊断与推测的诊断不符，并对后续治疗产生了重大影响。
