Novel glucoalkaloids from Rauwolfia cell cultures--acetylrauglucine and related glucosides. - Suppr | 超能文献

Novel glucoalkaloids from Rauwolfia cell cultures--acetylrauglucine and related glucosides.

作者信息

Ruyter C M, Schübel H, Stöckigt J

机构信息

Institut für Pharmazeutische Biologie, Universität München, Bundesrepublik Deutschland.

出版信息

Z Naturforsch C J Biosci. 1988 Jul-Aug;43(7-8):479-84. doi: 10.1515/znc-1988-7-801.

DOI:10.1515/znc-1988-7-801

Abstract

From cell suspension cultures of Rauwolfia serpentina grown in an optimized production medium for the glucoalkaloid raucaffricine, a novel glucoalkaloid was isolated and identified as 17-O-acetyl-21-O-beta-D-glucopyranosyl-ajmaline (acetylrauglucine). This alkaloid is formed in very small amounts (less than 5 x 10(-4)%). The biogenetically related N alpha-demethylated base (acetyl-nor-rauglucine) and the deacetyl product rauglucine have also been detected in culture extracts. In addition 21(R)-(beta-D-glucopyranosyl)-hydroxy-sarpagan-17-al has been isolated and identified as an artifact which originates from raucaffricine.

摘要

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