病毒吸附到细胞表面对感染复数输入的依赖性。

Dependence of virus adsorption to the cell surface on the input multiplicity of infection.

作者信息

Lipkind M, Urbakh V

机构信息

Kimron Veterinary Institute, Beit Dagan, Israel.

出版信息

Zentralbl Bakteriol Mikrobiol Hyg A. 1988 Nov;269(4):501-5. doi: 10.1016/s0176-6724(88)80072-5.

DOI:10.1016/s0176-6724(88)80072-5

PMID:3223130

Abstract

A state of "saturation" of the cell surface ensues when only 5-10% of the cell surface is "covered" by the adsorbed virions. Hence, this state cannot be explained by an "overcrowding effect" caused by the virions attached to the cell surface. A hypothesis of heterogeneity of the cell surface with regard to the virus absorbtion ("the domain hypothesis") is suitable for explanation.

摘要

当细胞表面仅5%-10%被吸附的病毒粒子“覆盖”时，细胞表面就会出现“饱和”状态。因此，这种状态无法用附着在细胞表面的病毒粒子所引起的“过度拥挤效应”来解释。关于病毒吸附的细胞表面异质性假说（“区域假说”）适用于解释这一现象。