Verrotti A, Blasetti A, Tumini S, Chiarelli F, Morgese G
Clinica Pediatrica, Università di Chieti, Italy.
Acta Diabetol Lat. 1988 Apr-Jun;25(2):173-7. doi: 10.1007/BF02581382.
Many authors have described abnormalities of calcium homeostasis in type I diabetes mellitus, but data in the literature are conflicting. Consequently we studied calcium, phosphorus and magnesium (in serum and urine), parathyroid hormone, calcitonin and 25-hydroxyvitamin D (25-OHD) levels in 21 prepubertal diabetic patients and in 21 sex- and age-matched controls. We did not find any significant difference of all the aforementioned parameters between diabetics and controls. Also the value of 25-OHD was similar in diabetic and healthy subjects (24.33 +/- 6.04 vs 22.09 +/- 5.01 ng/ml). The results suggest that the principal parameters of calcium metabolism are normal in prepubertal diabetic children.
许多作者都描述过I型糖尿病患者钙稳态异常，但文献中的数据相互矛盾。因此，我们研究了21名青春期前糖尿病患者以及21名性别和年龄匹配的对照组的钙、磷和镁（血清和尿液中）、甲状旁腺激素、降钙素和25-羟维生素D（25-OHD）水平。我们未发现糖尿病患者与对照组在上述所有参数上有任何显著差异。糖尿病患者和健康受试者的25-OHD值也相似（分别为24.33±6.04和22.09±5.01 ng/ml）。结果表明，青春期前糖尿病儿童的钙代谢主要参数正常。
