Duzguner Soner, Turkmen Osman, Kimyon Gunsu, Duzguner Ipek Nur, Karalok Alper, Basaran Derman, Tasci Tolga, Ureyen Isin, Turan Taner
Department of Gynecology and Obstetrics, Bahcelievler State Hospital, Istanbul, Turkey.
Department of Gynecologic Oncology, Etlik Zubeyde Hanim Women's Health Training and Research Hospital, Ankara, Turkey.
North Clin Istanb. 2019 Jul 3;7(1):60-64. doi: 10.14744/nci.2019.17048. eCollection 2020.
In this study, we analyzed surgico-pathologic factors of mucinous type endometrial carcinoma and examined its frequency of recurrence.
In this study, eleven cases, definitely diagnosed as pure mucinous type endometrium carcinoma between January 1993 and May 2013, were reviewed.
Of 1640 women with endometrium carcinoma, 11 (0.67%) of them had a mucinous cell type. Mean age of the study group was 55 years. According to the FIGO 2009, 10 (90.9%) cases were evaluated as stage I and 1 (9.1%) as stage IIIC1. The presence of lymph node metastasis was noticed in only one (12.5%) of eight patients who underwent lymphadenectomy. In this case, metastasis was detected in the pelvic lymph node. Four patients underwent adjuvant therapy as pelvic radiotherapy. Median follow-up time was 50 months (range, 5-84). Recurrence was observed in one (9.1%) patient with stage IIIC1 endometrial cancer in 30 months after primary surgery. The site of recurrence was only in the upper abdominal region.
Based on our study, mucinous endometrial carcinoma has good prognostic factors, and long term survival can be achieved surgically alone in patients with stage I.
在本研究中，我们分析了黏液型子宫内膜癌的外科病理因素，并研究了其复发频率。
本研究回顾了1993年1月至2013年5月间确诊为纯黏液型子宫内膜癌的11例病例。
在1640例子宫内膜癌女性患者中，11例（0.67%）为黏液细胞型。研究组的平均年龄为55岁。根据2009年国际妇产科联盟（FIGO）分期，10例（90.9%）为Ⅰ期，1例（9.1%）为ⅡIC1期。在接受淋巴结切除术的8例患者中，仅1例（12.5%）发现有淋巴结转移。在此病例中，盆腔淋巴结发现转移。4例患者接受了盆腔放疗辅助治疗。中位随访时间为50个月（范围5 - 84个月）。1例ⅡIC1期子宫内膜癌患者在初次手术后30个月出现复发。复发部位仅在上腹部区域。
基于我们的研究，黏液型子宫内膜癌具有良好的预后因素，Ⅰ期患者仅通过手术即可实现长期生存。
