Schwaiger A, Mühlberger V, Wiedermann C J, Baumgartner H, Knapp E
Universitätsklinik für Innere Medizin Innsbruck.
Acta Med Austriaca. 1988;15(3):83-6.
Plasma catecholamine levels were obtained during diagnostic heart catheterization from pulmonary artery and aorta before and after injection of contrast medium in 31 patients with coronary heart disease and in 18 normals. The most striking difference between both groups is a significant decline of norepinephrine concentration in aortas after injection of contrast medium in the normals (from 296 +/- 24 [mean +/- SEM] to 225 +/- 21 pg/ml [p less than 0.01]) and no change in patients with coronary heart disease. The cause seems to be rather increased elimination than a decrease of secretion of norepinephrine. Adrenalin shows only partially similar results. Further studies will have to show, what could be the reason for these different reactions of catecholamine level in normals and in patients with coronary heart disease.
在31例冠心病患者和18名正常人进行诊断性心脏导管插入术期间,于注射造影剂前后从肺动脉和主动脉获取血浆儿茶酚胺水平。两组之间最显著的差异是,正常人群注射造影剂后主动脉中去甲肾上腺素浓度显著下降(从296±24[均值±标准误]降至225±21 pg/ml[p<0.01]),而冠心病患者则无变化。原因似乎是去甲肾上腺素的消除增加而非分泌减少。肾上腺素仅呈现部分相似结果。进一步研究将揭示正常人和冠心病患者儿茶酚胺水平出现这些不同反应的原因。