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乳房植入物相关间变性大细胞淋巴瘤:情绪影响和心理支持指南。

Breast implant-associated anaplastic large cell lymphoma: emotional impact and guidelines for psychological support.

机构信息

Department of Oncology and Hematoncology (DIPO), University of Milan, Via Festa del Perdono 7, 20122, Milan, Italy.

Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

出版信息

Breast Cancer Res Treat. 2020 May;181(1):221-224. doi: 10.1007/s10549-020-05601-w. Epub 2020 Mar 31.

DOI:10.1007/s10549-020-05601-w
PMID:32232699
Abstract

PURPOSE

During the last two decades, the number of breast implants used in aesthetic, oncologic, and risk-reducing surgery has increased substantially mainly due to the improvement and confirmed safety of these devices. Since the identification of the first case of anaplastic large cell lymphoma associated with a breast implant (BIA-ALCL) 20 years ago, there has been an increase in the number of reports of this very rare disease, demonstrating a clear association with breast implants. While the majority of cases are localized and cured by implant removal and full capsulectomy, a small percentage require chemotherapy and the mortality rate is very low. Nevertheless, the evidence linking BIA-ALCL to implant surface texturing has raised concerns about the long-term safety of these devices resulting in patient and regulatory authority concerns globally.

METHODS AND RESULTS

In this commentary, we report the current debate on BIA-ALCL and the main European government's actions, with a special focus on the emotional impact that media coverage has on cancer patients. We comment the emotional impact of such risk for patients with breast implant, the hard process of patient's acceptance for mastectomy and reconstructive surgery, and how this is an essential part of recovery and return to the normal living for many women.

CONCLUSION

We conclude by providing guidelines for patient-physician communication and patients' psychological support on this topic of delicate actuality. Our contribution aims at guiding the medical community in managing risk communication about BIA-ALCL with a multidisciplinary approach, according to the most recently available published evidence.

摘要

目的

在过去的二十年中,由于这些设备的改进和安全性得到证实,用于美容、肿瘤学和降低风险手术的乳房植入物数量大幅增加。自 20 年前首例与乳房植入物相关的间变性大细胞淋巴瘤(BIA-ALCL)病例被确认以来,这种非常罕见疾病的报告数量有所增加,表明其与乳房植入物存在明确关联。虽然大多数病例通过移除植入物和完整包膜切除术即可局部治愈,但仍有一小部分病例需要化疗,死亡率非常低。然而,将 BIA-ALCL 与植入物表面纹理联系起来的证据引发了对这些设备长期安全性的担忧,这导致了全球范围内患者和监管机构的关注。

方法和结果

在这篇评论中,我们报告了目前关于 BIA-ALCL 的争论以及主要欧洲政府的行动,特别关注媒体报道对癌症患者的情绪影响。我们评论了乳房植入物患者面临这种风险的情绪影响、患者接受乳房切除术和重建手术的艰难过程,以及这对许多女性的康复和回归正常生活是多么重要的一部分。

结论

我们的结论是提供关于这一具有微妙现实意义的话题的医患沟通和患者心理支持的指南。我们的贡献旨在根据最新可用的已发表证据,指导医学界以多学科方法管理 BIA-ALCL 的风险沟通。

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