O'Brien K P, Glaudin V
Neuropsychology Department, Barrow Neurological Institute, Phoenix, Arizona.
Acta Psychiatr Scand. 1988 Aug;78(2):113-20. doi: 10.1111/j.1600-0447.1988.tb06311.x.
Identical principal components factor analyses of total Hamilton Rating Scale for Depression scores were conducted for two separate sub-samples (N = 183 and N = 182) drawn from the same clinic population of moderately depressed outpatients. A comparison of the two factor analyses revealed substantial agreement for four factors across the two sub-samples (i.e., four factors from the first sub-sample correlated at least 0.80 with a homologous dimension in the second sub-sample). The four factors were labelled Somatic Complaints, Anorexia, Sleep Disturbance, and Agitation/Retardation. Some additional factors emerged in the analysis of one sub-sample but failed to appear in the other. Overall, these results suggest that the HRS exhibited a relatively stable factorial structure based on a large sample of outpatients with unipolar depressive disorders. Methodological problems with earlier research are discussed in light of the current findings.
对来自同一临床门诊中度抑郁症患者群体的两个独立子样本（N = 183和N = 182）进行了汉密尔顿抑郁量表总分的相同主成分因子分析。对这两个因子分析的比较显示，两个子样本在四个因子上有实质性的一致性（即第一个子样本的四个因子与第二个子样本中的同源维度至少有0.80的相关性）。这四个因子分别被标记为躯体主诉、厌食、睡眠障碍和激越/迟缓。在一个子样本的分析中出现了一些其他因子，但在另一个子样本中未出现。总体而言，这些结果表明，基于大量单相抑郁症门诊患者样本，汉密尔顿抑郁量表呈现出相对稳定的因子结构。根据当前研究结果讨论了早期研究中的方法学问题。
