Van Pelt Q, Stragier E, Roelandt P, Van Cutsem E
Digestive Oncology Department, University Hospitals Leuven, Belgium.
Acta Gastroenterol Belg. 2020 Jan-Mar;83(1):47-50.
Posterior reversible encephalopathy syndrome (PRES) is a rare disorder with multiple causes but potentially caused by chemotherapy. We present 3 cases of PRES of whom 2 are presumably caused by oxaliplatin and one by regorafenib. We discuss in this article the 3 cases individually and we summarize in the discussion the proposed theories in the literature of possible pathophysiological mechanisms. Our main goal of this article is to increase awareness among physicians when they are confronted with patients on chemotherapy who present with (sub)acute encephalopathy.
后部可逆性脑病综合征（PRES）是一种病因多样的罕见疾病，但可能由化疗引起。我们报告3例PRES病例，其中2例可能由奥沙利铂引起，1例由瑞戈非尼引起。本文分别讨论这3例病例，并在讨论中总结文献中提出的可能病理生理机制的理论。本文的主要目的是提高医生在面对接受化疗且出现（亚）急性脑病的患者时的认识。
