乙醇对运动表现及与运动相关脑电位的急性影响。

Acute effects of ethanol on motor performance and movement-related brain potentials.

作者信息

Rohrbaugh J W, Stapleton J M, Frowein H W, Adinoff B, Varner J L, Lane E A, Eckardt M J, Linnoila M

机构信息

Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892.

出版信息

Adv Alcohol Subst Abuse. 1988;7(3-4):53-7. doi: 10.1300/J251v07n03_09.

DOI:10.1300/J251v07n03_09

PMID:3223435

Abstract

The acute effects of ethanol on skilled motor functions were examined in male social drinkers, under four doses ranging from 0 (placebo) to 1.05 g/kg lean body weight. The movement entailed a forewarned choice transitive motion of the arm and hand, aimed at a flanking target. Performance measures disclosed only small effects of ethanol on speed and accuracy of movement. The simultaneously-recorded movement-related brain potentials disclosed decreased involvement of frontal and posterior brain areas, suggesting that ethanol disrupted the planning and regulation of movement despite the overall preservation of reaction speed.

摘要

研究了乙醇对男性社交饮酒者熟练运动功能的急性影响，剂量范围为0（安慰剂）至1.05克/千克瘦体重，共四种剂量。该动作包括手臂和手部事先得到提示的选择传递运动，目标是侧面的一个靶点。性能测量结果显示，乙醇对运动速度和准确性的影响很小。同时记录的与运动相关的脑电信号显示，额叶和后脑区域的参与度降低，这表明尽管反应速度总体保持，但乙醇扰乱了运动的计划和调节。