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超声引导下筋膜平面阻滞用于非麻醉医师行乳腺癌手术:功能结局和获益。

Ultrasound-guided Interfascial Plane Blocks for Non-anesthesiologists in Breast Cancer Surgery: Functional Outcomes and Benefits.

机构信息

Department of Breast Surgery, University Campus Bio-Medico, Rome, Italy.

Department of Breast Surgery, University Campus Bio-Medico, Rome, Italy

出版信息

Anticancer Res. 2020 Apr;40(4):2231-2238. doi: 10.21873/anticanres.14185.

DOI:10.21873/anticanres.14185
PMID:32234919
Abstract

AIM

Acute post-operative pain following modified radical mastectomy (MRM) in patients with breast cancer is challenging for anesthesiologists. This study aimed to prospectively compare the quality outcome of interfascial plane blocks performed with ultrasound guidance, and evaluate the consequences of sharing tasks with the breast surgeon.

PATIENTS AND METHODS

The study involved 255 patients scheduled for unilateral MRM, who were divided into two groups: Pecs group: General anesthesia plus ultrasound-guided modified pectoral nerves blocks type I and II, including serratus and parasternal infiltration according to surgical requirements; and Control group: general anesthesia only. Quality was evaluated based on perioperative opioid consumption, reported pain intensity, rescue analgesic requirement, side-effects and length of hospital stay. Moreover, a breast surgeon with expertise in ultrasound-guided breast biopsy was trained to perform the blocks. The patient benefits from regional anesthesia delivered by a non-anesthesiologist were assessed.

RESULTS

Significant reductions were noted in all of the following: Intraoperative opioid consumption (p<0.001), Numerating Rating Scale pain scores taken 0 and 24 h after surgery (p<0.001), post-operative analgesic administration (p<0.001), nausea and vomiting at 0, 6, and 12-h intervals (p<0.05), and hospital stay (p<0.001) were observed in the Pecs group compared with the control group. Furthermore, data obtained from patients receiving the block from the surgeon showed comparable benefits with no complications.

CONCLUSION

Interfascial plane blocks may be an important alternative protocol in MRM, enhancing patient safety and cost benefits. Improvements in cross-disciplinary expertise through flexibility in the training of professionals with other backgrounds may provide effective analgesia and favorable outcomes.

摘要

目的

乳腺癌改良根治术后(MRM)患者的急性术后疼痛对麻醉医师来说是一个挑战。本研究旨在前瞻性比较超声引导下筋膜平面阻滞的质量结果,并评估与乳腺外科医生分担任务的后果。

患者和方法

本研究纳入了 255 名计划接受单侧 MRM 的患者,将其分为两组:胸肌组:全身麻醉加超声引导下改良胸神经阻滞 I 型和 II 型,根据手术要求包括肋间肌和胸骨旁浸润;对照组:全身麻醉。根据围手术期阿片类药物的使用、报告的疼痛强度、需要解救性镇痛、副作用和住院时间来评估质量。此外,还培训了一位精通超声引导下乳腺活检的乳腺外科医生来进行阻滞。评估了由非麻醉医生提供区域麻醉的患者获益。

结果

与对照组相比,胸肌组的所有以下方面均显著减少:术中阿片类药物的使用(p<0.001)、术后 0 小时和 24 小时的数字评分量表疼痛评分(p<0.001)、术后镇痛药物的使用(p<0.001)、术后 0 小时、6 小时和 12 小时的恶心和呕吐(p<0.05)以及住院时间(p<0.001)。此外,从接受外科医生进行阻滞的患者中获得的数据显示,无并发症且具有相似的获益。

结论

筋膜平面阻滞可能是 MRM 的重要替代方案,可提高患者安全性和成本效益。通过具有其他背景的专业人员的培训灵活性,提高跨学科专业知识,可能提供有效的镇痛和良好的结果。

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