Pascarella Giuseppe, Costa Fabio, Nonnis Giulia, Strumia Alessandro, Sarubbi Domenico, Schiavoni Lorenzo, Di Pumpo Annalaura, Mortini Lara, Grande Stefania, Attanasio Andrea, Gadotti Giovanni, De Cassai Alessandro, Mattei Alessia, Nenna Antonio, Chello Massimo, Cataldo Rita, Agrò Felice Eugenio, Carassiti Massimiliano
Unit of Anaesthesia and Intensive Care, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.
Unit of Anaesthesia and Intensive Care, Ospedale dei Castelli, Ariccia, 00040 Rome, Italy.
J Clin Med. 2023 Mar 6;12(5):2060. doi: 10.3390/jcm12052060.
Ultrasound guided parasternal block is a regional anaesthesia technique targeting the anterior branches of intercostal nerves, which supply the anterior thoracic wall. The aim of this prospective study is to assess the efficacy of parasternal block to manage postoperative analgesia and reduce opioid consumption in patients undergoing cardiac surgery throughout sternotomy. A total of 126 consecutive patients were allocated to two different groups, receiving (Parasternal group) or not (Control group) preoperative ultrasound guided bilateral parasternal block with 20 mL of 0.5% ropivacaine per side. The following data were recorded: postoperative pain expressed by a 0-10 numeric rating scale (NRS), intraoperative fentanyl consumption, postoperative morphine consumption, time to extubation and perioperative pulmonary performance at incentive spirometry. Postoperative NRS was not significantly different between Parasternal and Control groups with a median (IQR) of 2 (0-4.5) vs. 3 (0-6) upon awakening ( = 0.07); 0 (0-3) vs. 2 (0-4) at 6 h ( = 0.46); 0 (0-2) vs. 0 (0-2) at 12 h ( = 0.57). Postoperative morphine consumption was similar among groups. However, intraoperative fentanyl consumption was significantly lower in the Parasternal group [406.3 ± 81.6 mcg vs. 864.3 ± 154.4, ( < 0.001)]. Parasternal group showed shorter times to extubation [(191 ± 58 min vs. 305 ± 72 min, ()] and better performance at incentive spirometer with a median (IQR) of 2 raised balls (1-2) vs. 1 (1-2) after awakening ( = 0.04). Ultrasound guided parasternal block provided an optimal perioperative analgesia with a significant reduction in intraoperative opioid consumption, time to extubation and a better postoperative performance at spirometry when compared to the Control group.
超声引导下胸骨旁阻滞是一种针对肋间神经前支的区域麻醉技术,这些神经为胸前壁提供血液供应。这项前瞻性研究的目的是评估胸骨旁阻滞在接受开胸心脏手术患者中管理术后镇痛和减少阿片类药物消耗的效果。总共126例连续患者被分配到两个不同的组,一组接受(胸骨旁组)或不接受(对照组)术前超声引导下双侧胸骨旁阻滞,每侧注射20 mL 0.5%罗哌卡因。记录了以下数据:用0至10数字评分量表(NRS)表示的术后疼痛、术中芬太尼消耗量、术后吗啡消耗量、拔管时间以及激励肺活量测定时的围手术期肺功能。胸骨旁组和对照组术后NRS无显著差异,苏醒时中位数(IQR)分别为2(0 - 4.5)和3(0 - 6)(P = 0.07);6小时时分别为0(0 - 3)和2(0 - 4)(P = 0.46);12小时时分别为0(0 - 2)和0(0 - 2)(P = 0.57)。各组术后吗啡消耗量相似。然而,胸骨旁组术中芬太尼消耗量显著更低[406.3 ± 81.6 mcg对864.3 ± 154.4,(P < 0.001)]。胸骨旁组拔管时间更短[(191 ± 58分钟对305 ± 72分钟,(P)],苏醒后激励肺活量测定表现更好,中位数(IQR)为2个升高球(1 - 2)对1(1 - 2)(P = 0.04)。与对照组相比,超声引导下胸骨旁阻滞提供了最佳的围手术期镇痛,术中阿片类药物消耗量显著减少,拔管时间缩短,术后肺活量测定表现更好。