Department of Hepato-Biliary Pancreatic Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
Department of Hepato-Biliary Pancreatic Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
Anticancer Res. 2020 Apr;40(4):2297-2301. doi: 10.21873/anticanres.14195.
BACKGROUND/AIM: Pancreatic surgery is associated with a high risk of developing deep venous thrombosis (DVT) and malnutrition. We aimed to evaluate the factors predicting the development of DVT, focusing on nutrition assessment tools.
One hundred patients who underwent pancreatic surgery were postoperatively examined for DVT. We assessed the risk factors for the development of DVT after surgery.
Postoperative DVT was detected in 11 patients (11%). Patients who developed DVT after surgery were significantly older (p=0.016) and had higher preoperative D-dimer levels (p=0.005) than those who did not. The preoperative prognostic nutritional index (PNI) was mostly associated with the development of DVT (p=0.079). Furthermore, PNI ≤44.3, BUN >20 mg/dl, D-dimer ≥1.9 μg/ml were independent predictors for the development of DVT after surgery.
A poor nutrition status and dehydration should be preoperatively improved for patients who are identified, as having a high risk of developing DVT after pancreatic surgery.
背景/目的：胰腺手术后深静脉血栓形成（DVT）和营养不良的风险很高。我们旨在评估预测 DVT 发展的因素，重点关注营养评估工具。
对 100 例行胰腺手术的患者进行术后 DVT 检查。我们评估了手术后 DVT 发展的危险因素。
术后 11 例（11%）患者发生 DVT。与未发生 DVT 的患者相比，术后发生 DVT 的患者年龄明显更大（p=0.016），术前 D-二聚体水平更高（p=0.005）。术前预后营养指数（PNI）与 DVT 的发生最相关（p=0.079）。此外，PNI≤44.3、BUN＞20mg/dl、D-二聚体≥1.9μg/ml 是胰腺手术后 DVT 发生的独立预测因素。
对于被识别为有高风险发生胰腺手术后 DVT 的患者，应在术前改善营养状况和脱水情况。
