Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Centre of Reproductive Medicine and Andrology, University of Münster, Münster, Germany.
Eur J Endocrinol. 2020 Jun;182(6):R101. doi: 10.1530/EJE-19-0903.
Sexual function is an important component of either general health and quality of life in both genders. Many studies have focused on the different risk factors for sexual dysfunctions, proving an association with several medical conditions. Endocrine disorders have been often mentioned in the pathogenesis of female and male sexual dysfunctions; however, particularly in women, sexual function is rarely addressed during clinical, in general, and endocrinological, in particular, consultations. As a thorough diagnosis is required in order to provide an adequately tailored treatment, knowing how each endocrine dysfunction can impair sexual health is of the utmost importance, considering the high prevalence of conditions such as disorders of pituitary, thyroid, adrenal, gonads, as well as metabolic disorders. We performed a thorough review of existing literature on the different mechanisms involved in the pathogenesis of female sexual dysfunctions secondary to endocrine disorders in order to provide an up-to-date reference.
性功能是两性普遍健康和生活质量的重要组成部分。许多研究都集中在不同的性功能障碍风险因素上,证明与许多医学疾病有关。内分泌紊乱在女性和男性性功能障碍的发病机制中经常被提及;然而,特别是在女性中,性功能在临床,一般来说,和内分泌学咨询中很少被提及。由于需要进行彻底的诊断以便提供量身定制的治疗,了解每种内分泌功能障碍如何损害性健康是非常重要的,因为诸如垂体、甲状腺、肾上腺、性腺疾病以及代谢紊乱等情况的患病率很高。我们对涉及内分泌紊乱引起的女性性功能障碍发病机制的不同机制的现有文献进行了全面回顾,以便提供最新的参考。