Pană Ana-Maria, Ordodi Valentin, Rusu Gerlinde, Gherman Vasile, Bandur Geza, Rusnac Lucian-Mircea, Dumitrel Gabriela-Alina
Faculty of Industrial Chemistry and Environmental Engineering, Politehnica University Timişoara, 6 Vasile Pȃrvan bvd., 300223 Timişoara, Romania.
Faculty of Civil Engineering, Politehnica University Timişoara, 2 Traian Lalescu Str, 300223 Timisoara, Romania.
Polymers (Basel). 2020 Mar 22;12(3):704. doi: 10.3390/polym12030704.
Glycopolymers are polymers with sugar moieties which display biodegradable and/or biocompatible character. They have emerged as an environmentally-friendly solution to classical synthetic polymers and have attracted significant research interest in the past years. Herein, we present the synthesis of a D-mannose based glycopolymer with biodegradable features. The glycopolymer was synthesized by radical copolymerization between a D-mannose oligomer bearing polymerizable double bonds and 2-hydroxypropyl acrylate, in a weight ratio of 1:2. The copolymerization kinetics was investigated by differential scanning calorimetry (DSC) and the activation energy of the process was comparatively assessed by Kissinger-Akahira-Sunose and Flynn-Wall-Ozawa methods. The obtained glycopolymer displayed good thermal behavior, fact proven by thermogravimetrical (TG) analysis and it was submitted to biodegradation inside a bioreactor fed with water from the Bega River as the source of microbial inoculum. The glycopolymer sample degraded by approximately 60% in just 23 days. The biodegradation pattern of the glycopolymer was successfully fitted against a modified sigmoidal exponential function. The kinetic model coefficients and its accuracy were calculated using Matlab and the correlation coefficient is more than promising. The changes inside glycopolymer structure after biodegradation were studied using TG and FTIR analyses, which revealed that the sugar moiety is firstly attacked by the microbial consortia as nutrient source for proliferation.
糖聚合物是带有糖部分的聚合物，具有可生物降解和/或生物相容性。它们已成为传统合成聚合物的一种环保替代品，并在过去几年中引起了广泛的研究兴趣。在此，我们展示了一种具有可生物降解特性的基于D-甘露糖的糖聚合物的合成。该糖聚合物是通过带有可聚合双键的D-甘露糖低聚物与丙烯酸2-羟丙酯以1:2的重量比进行自由基共聚合成的。通过差示扫描量热法（DSC）研究了共聚动力学，并通过基辛格-赤平-ose法和弗林-沃尔-小泽法对该过程的活化能进行了比较评估。所获得的糖聚合物表现出良好的热性能，热重分析（TG）证实了这一点，并且它在以贝加河的水作为微生物接种源的生物反应器中进行了生物降解。糖聚合物样品在短短23天内降解了约60%。糖聚合物的生物降解模式成功地拟合了一个修正的S形指数函数。使用Matlab计算了动力学模型系数及其准确性，相关系数非常可观。使用TG和FTIR分析研究了生物降解后糖聚合物结构的变化，结果表明糖部分首先受到微生物群落的攻击，作为其增殖的营养源。
