Pileire B, Moutet J P, Bangou J, Ragoucy-Sengler C M
Laboratoire de Biochimie, INSERM-SASD, Centre Hospitalier Régional et Universitaire, Pointe a Pitre, Guadeloupe.
Ann Biol Clin (Paris). 1988;46(9):719-21.
The authors compare the relative validity of HbA1c and fructosamine as indices of long-term blood glucose levels in population with a common occurrence of haemoglobinopathies. HbA1c levels in patients with haemoglobinopathies do not reflect the glucidic status of patients when compared to HbA1c levels in reference population. Validity of the fructosamine assay allows its potential use as a mass screening test for diabetes in these populations (USA, Africa, Caribbean...).
作者比较了糖化血红蛋白(HbA1c)和果糖胺作为血红蛋白病常见人群长期血糖水平指标的相对有效性。与参考人群的HbA1c水平相比,血红蛋白病患者的HbA1c水平不能反映患者的糖代谢状态。果糖胺检测的有效性使其有可能作为这些人群(美国、非洲、加勒比地区等)糖尿病大规模筛查的检测方法。