Universidade Federal de Minas Gerais. Belo Horizonte, Minas Gerais, Brazil.
Rev Bras Enferm. 2020 Mar 30;73(2):e20180757. doi: 10.1590/0034-7167-2018-0757. eCollection 2020.
To investigate the association between analgesia during labor and occurrence of neonatal outcomes.
Retrospective cohort study with medical records of 850 parturient. The exposure variable of interest was receiving pharmacological analgesia during labor and neonatal outcomes were: one- and five-minute Apgar, resuscitation maneuvers and referral of the newborn to Neonatal ICU. A logistic regression was carried out to obtain Odds Ratios and 95% confidence interval, with adjustment for confounding factors.
Among the women studied, 35% received analgesia and this use was associated with a greater chance of neonatal outcomes such as one-minute Apgar < 7 (p <0.0001), resuscitation maneuvers (p <0.001) and referral to the Neonatal ICU (p = 0.004), mostly were among low-risk pregnant women, even after adjustments.
The use of pharmacological analgesia during labor is associated with one-minute Apgar < 7, resuscitation maneuvers and referral to the Neonatal ICU.
研究分娩时镇痛与新生儿结局发生的关系。
对 850 例分娩产妇的病历进行回顾性队列研究。感兴趣的暴露变量为分娩时接受药物镇痛，新生儿结局为：1 分钟和 5 分钟 Apgar 评分、复苏操作和将新生儿转至新生儿 ICU。进行逻辑回归以获得优势比和 95%置信区间，并调整混杂因素。
在所研究的女性中，35%接受了镇痛，这与新生儿结局如 1 分钟 Apgar < 7（p <0.0001）、复苏操作（p <0.001）和转至新生儿 ICU（p = 0.004）的发生几率增加有关，这些结局主要发生在低风险孕妇中，即使在调整后也是如此。
分娩时使用药物镇痛与 1 分钟 Apgar < 7、复苏操作和转至新生儿 ICU 有关。
