Universidade Federal de Minas Gerais. Belo Horizonte, Minas Gerais, Brazil.
Rev Bras Enferm. 2020 Jul 1;73(5):e20180757. doi: 10.1590/0034-7167-2018-0757. eCollection 2020.
To investigate the association between analgesia during labor and occurrence of neonatal outcomes.
Retrospective cohort study with medical records of 850 parturient. The exposure variable of interest was receiving pharmacological analgesia during labor and neonatal outcomes were: one- and five-minute Apgar, resuscitation maneuvers and referral of the newborn to Neonatal ICU. A logistic regression was carried out to obtain Odds Ratios and 95% confidence interval, with adjustment for confounding factors.
Among the women studied, 35% received analgesia and this use was associated with a greater chance of neonatal outcomes such as one-minute Apgar < 7 (p <0.0001), resuscitation maneuvers (p <0.001) and referral to the Neonatal ICU (p = 0.004), mostly were among low-risk pregnant women, even after adjustments.
The use of pharmacological analgesia during labor is associated with one-minute Apgar < 7, resuscitation maneuvers and referral to the Neonatal ICU.
探讨分娩镇痛与新生儿结局发生的关系。
这是一项回顾性队列研究，纳入了 850 名产妇的病历。研究的暴露变量为分娩时使用药物性镇痛，新生儿结局包括：1 分钟和 5 分钟时的阿普加评分、复苏操作和将新生儿转至新生儿重症监护病房（NICU）。采用逻辑回归分析得到比值比（OR）和 95%置信区间（CI），并进行了混杂因素调整。
在所研究的女性中，35%的人接受了镇痛，这与新生儿结局如 1 分钟阿普加评分<7（p<0.0001）、复苏操作（p<0.001）和转至新生儿 NICU（p=0.004）的几率增加有关，且主要发生在低危孕妇中，即使进行了调整。
分娩时使用药物性镇痛与 1 分钟阿普加评分<7、复苏操作和转至新生儿 NICU 有关。
