Gossett K A, McCoy D J, Jowett P L, Kearney M T
Department of Veterinary Pathology, Louisiana State University, Baton Rouge 70803.
Am J Vet Res. 1988 Sep;49(9):1601-4.
Nitrofurazone solution containing 0.2% nitrofurazone and 99.8% polyethylene glycol was given to 4 healthy horses (2 L in 2 L of lactated Ringer solution, intraperitoneally). Horses developed hypovolemia, hyperosmolality, and mixed respiratory and metabolic acidosis. These changes were largely attributable to polyethylene glycol, but a contribution of nitrofurazone cannot be excluded. Intraperitoneal infusion of nitrofurazone solution in horses is contraindicated.
将含有0.2%呋喃西林和99.8%聚乙二醇的呋喃西林溶液给予4匹健康马（2升溶于2升乳酸林格液中，腹腔内注射）。马匹出现血容量不足、高渗状态以及混合性呼吸性和代谢性酸中毒。这些变化很大程度上归因于聚乙二醇，但不能排除呋喃西林的作用。腹腔内注射呋喃西林溶液对马是禁忌的。
